Evaluation of abnormal liver tests

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Abstract

Serum liver tests are important but often problematic in evaluating patients with and without symptoms of hepatic disease. The common term "liver function tests" is misleading because most tests used in clinical practice measure hepatocellular damage not function. True liver function tests are those that measure synthesis of proteins made by the liver (albumin, clotting factors) or the liver's capacity to metabolize drugs. A commonly ordered panel of automated tests includes bilirubin, aminotransferases, alkaline phosphatase, and γ-glutamyl transpeptidase. This article reviews patterns of elevated enzyme values encountered in liver diseases and their diagnostic limitations and provides an algorithm for evaluating abnormal liver test results.

Original languageEnglish (US)
Pages (from-to)1-12
Number of pages12
JournalClinical Cornerstone
Volume3
Issue number6
DOIs
Publication statusPublished - Jan 1 2001

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ASJC Scopus subject areas

  • Medicine(all)

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