Evaluation of abnormal liver tests

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Serum liver tests are important but often problematic in evaluating patients with and without symptoms of hepatic disease. The common term "liver function tests" is misleading because most tests used in clinical practice measure hepatocellular damage not function. True liver function tests are those that measure synthesis of proteins made by the liver (albumin, clotting factors) or the liver's capacity to metabolize drugs. A commonly ordered panel of automated tests includes bilirubin, aminotransferases, alkaline phosphatase, and γ-glutamyl transpeptidase. This article reviews patterns of elevated enzyme values encountered in liver diseases and their diagnostic limitations and provides an algorithm for evaluating abnormal liver test results.

Original languageEnglish (US)
Pages (from-to)1-12
Number of pages12
JournalClinical Cornerstone
Volume3
Issue number6
DOIs
StatePublished - Jan 1 2001

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Liver
Liver Function Tests
Blood Coagulation Factors
gamma-Glutamyltransferase
Transaminases
Bilirubin
Alkaline Phosphatase
Liver Diseases
Albumins
Enzymes
Serum
Pharmaceutical Preparations
Proteins

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Evaluation of abnormal liver tests. / Rochling, Fedja A.

In: Clinical Cornerstone, Vol. 3, No. 6, 01.01.2001, p. 1-12.

Research output: Contribution to journalArticle

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