Epstein‐Barr virus: Experimental infection of Callithrix Jacchus marmosets

Lawrence Falk, Friedrich Deinhardt, Lauren Wolfe, Donald Johnson, Jo Hilgers, Guy De‐Thé

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27 Scopus citations

Abstract

Eight common marmoset monkeys (Callithrix jacchus) were inoculated with about 104 transforming units of B95‐8 virus; seven of the marmosets died 50‐111 days post inoculation and all seven showed microscopic and/or macroscopic lesions compatible with a diagnosis of lymphoproliferative disease. Low levels of anti‐VCA antibodies were detected in plasma from six marmosets. Attempts failed to establish continuous EBV‐carrying lymphoblastoid cell cultures by cultivation in vitro of circulating lymphocytes or minced lymphoid tissues obtained at necropsy.

Original languageEnglish (US)
Pages (from-to)785-788
Number of pages4
JournalInternational Journal of Cancer
Volume17
Issue number6
DOIs
StatePublished - Jun 15 1976

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ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Falk, L., Deinhardt, F., Wolfe, L., Johnson, D., Hilgers, J., & De‐Thé, G. (1976). Epstein‐Barr virus: Experimental infection of Callithrix Jacchus marmosets. International Journal of Cancer, 17(6), 785-788. https://doi.org/10.1002/ijc.2910170615