Epstein‐Barr virus

Experimental infection of Callithrix Jacchus marmosets

Lawrence Falk, Friedrich Deinhardt, Lauren Wolfe, Donald R Johnson, Jo Hilgers, Guy De‐Thé

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Eight common marmoset monkeys (Callithrix jacchus) were inoculated with about 104 transforming units of B95‐8 virus; seven of the marmosets died 50‐111 days post inoculation and all seven showed microscopic and/or macroscopic lesions compatible with a diagnosis of lymphoproliferative disease. Low levels of anti‐VCA antibodies were detected in plasma from six marmosets. Attempts failed to establish continuous EBV‐carrying lymphoblastoid cell cultures by cultivation in vitro of circulating lymphocytes or minced lymphoid tissues obtained at necropsy.

Original languageEnglish (US)
Pages (from-to)785-788
Number of pages4
JournalInternational Journal of Cancer
Volume17
Issue number6
DOIs
StatePublished - Jan 1 1976

Fingerprint

Callithrix
Virus Diseases
Lymphoid Tissue
Haplorhini
Cell Culture Techniques
Lymphocytes
Viruses
Antibodies

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Falk, L., Deinhardt, F., Wolfe, L., Johnson, D. R., Hilgers, J., & De‐Thé, G. (1976). Epstein‐Barr virus: Experimental infection of Callithrix Jacchus marmosets. International Journal of Cancer, 17(6), 785-788. https://doi.org/10.1002/ijc.2910170615

Epstein‐Barr virus : Experimental infection of Callithrix Jacchus marmosets. / Falk, Lawrence; Deinhardt, Friedrich; Wolfe, Lauren; Johnson, Donald R; Hilgers, Jo; De‐Thé, Guy.

In: International Journal of Cancer, Vol. 17, No. 6, 01.01.1976, p. 785-788.

Research output: Contribution to journalArticle

Falk, L, Deinhardt, F, Wolfe, L, Johnson, DR, Hilgers, J & De‐Thé, G 1976, 'Epstein‐Barr virus: Experimental infection of Callithrix Jacchus marmosets', International Journal of Cancer, vol. 17, no. 6, pp. 785-788. https://doi.org/10.1002/ijc.2910170615
Falk, Lawrence ; Deinhardt, Friedrich ; Wolfe, Lauren ; Johnson, Donald R ; Hilgers, Jo ; De‐Thé, Guy. / Epstein‐Barr virus : Experimental infection of Callithrix Jacchus marmosets. In: International Journal of Cancer. 1976 ; Vol. 17, No. 6. pp. 785-788.
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