Epidemiology, etiology, and management of Kawasaki disease: State of the art

K. B. Laupland, H. Dele Davies

Research output: Contribution to journalReview article

63 Citations (Scopus)

Abstract

Since its first description in Japan 30 years ago, Kawasaki disease has been reported worldwide. Although an infectious etiology is suspected based on the epidemiology and clinical features, a causative agent has not been identified. The majority of the morbidity and mortality associated with this condition is attributable to the development of coronary artery aneurysms. Treatment during the acute phase with intravenous immunoglobulin and acetylsalicylic acid results in significant reductions in coronary complications. The long-term management of patients with persistent coronary abnormalities is less well-defined. This article reviews the epidemiology, possible etiologies, and management of Kawasaki disease.

Original languageEnglish (US)
Pages (from-to)177-183
Number of pages7
JournalPediatric Cardiology
Volume20
Issue number3
DOIs
StatePublished - May 1 1999

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Mucocutaneous Lymph Node Syndrome
Epidemiology
Coronary Aneurysm
Intravenous Immunoglobulins
Aspirin
Coronary Vessels
Japan
Morbidity
Mortality
Therapeutics

Keywords

  • Coronary aneurysms
  • Epidemiology
  • Etiology
  • Kawasaki disease
  • Management

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Cardiology and Cardiovascular Medicine

Cite this

Epidemiology, etiology, and management of Kawasaki disease : State of the art. / Laupland, K. B.; Davies, H. Dele.

In: Pediatric Cardiology, Vol. 20, No. 3, 01.05.1999, p. 177-183.

Research output: Contribution to journalReview article

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