Endoscopic sinus surgery in cystic fibrosis: Do patients benefit from surgery?

Kristina W. Rosbe, Dwight T. Jones, Reza Rahbar, Thomas Lahiri, Andrew D. Auerbach

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

Objective: To examine the effects of endoscopic sinus surgery on the pulmonary status of cystic fibrosis (CF) patients through the objective parameters of steroid use, pulmonary function tests (PFTs), and inpatient hospital days (IHDs). Methods: Retrospective chart review of all patients with CF who underwent endoscopic sinus surgery from 1993 to 1999 at a tertiary care children's hospital. Preoperative pulmonary function, inhaler and steroid use, and IHDs were compared to postoperative parameters within a 1-year period. Results: Sixty-six patients, including eight lung transplant patients, underwent a total of 112 endoscopic sinus surgery procedures; 25 patients underwent more than one procedure. Patients were taking oral steroids preoperatively in 28% of procedures and inhaled steroids in 40%. Postoperatively, there was no statistically significant change in oral or inhaled steroid use, or in postoperative pulmonary function. If the index hospitalization, which was often for reasons not related to sinus disease, was considered part of the preoperative time period, endoscopic sinus surgery (ESS) was noted to result in a marked reduction (9.5 days (adjusted), P=0.001) in hospital days during the subsequent 6 months. If the date of the procedure alone was used to define pre- and postoperative time periods, the reduction in postoperative days was more modest and not statistically significant (3.5 days (adjusted), P=0.21). Conclusions: Although we found no statistically significant difference in PFTs, or steroid requirements following ESS, ESS may have resulted in a reduced need for hospitalization in the 6 months following the procedure. Future prospective studies in a larger number of patients and using more detailed outcome measures are needed to better evaluate the effects of endoscopic sinus surgery in pediatric patients with CF.

Original languageEnglish (US)
Pages (from-to)113-119
Number of pages7
JournalInternational Journal of Pediatric Otorhinolaryngology
Volume61
Issue number2
DOIs
StatePublished - Nov 1 2001

Fingerprint

Cystic Fibrosis
Steroids
Respiratory Function Tests
Lung
Inpatients
Hospitalization
Preoperative Period
Nebulizers and Vaporizers
Tertiary Healthcare
Postoperative Period
Outcome Assessment (Health Care)
Prospective Studies
Pediatrics
Transplants

Keywords

  • Cystic fibrosis
  • Endoscopic sinus surgery

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Otorhinolaryngology

Cite this

Endoscopic sinus surgery in cystic fibrosis : Do patients benefit from surgery? / Rosbe, Kristina W.; Jones, Dwight T.; Rahbar, Reza; Lahiri, Thomas; Auerbach, Andrew D.

In: International Journal of Pediatric Otorhinolaryngology, Vol. 61, No. 2, 01.11.2001, p. 113-119.

Research output: Contribution to journalArticle

Rosbe, Kristina W. ; Jones, Dwight T. ; Rahbar, Reza ; Lahiri, Thomas ; Auerbach, Andrew D. / Endoscopic sinus surgery in cystic fibrosis : Do patients benefit from surgery?. In: International Journal of Pediatric Otorhinolaryngology. 2001 ; Vol. 61, No. 2. pp. 113-119.
@article{7fc084131159484ba0cad78de289370c,
title = "Endoscopic sinus surgery in cystic fibrosis: Do patients benefit from surgery?",
abstract = "Objective: To examine the effects of endoscopic sinus surgery on the pulmonary status of cystic fibrosis (CF) patients through the objective parameters of steroid use, pulmonary function tests (PFTs), and inpatient hospital days (IHDs). Methods: Retrospective chart review of all patients with CF who underwent endoscopic sinus surgery from 1993 to 1999 at a tertiary care children's hospital. Preoperative pulmonary function, inhaler and steroid use, and IHDs were compared to postoperative parameters within a 1-year period. Results: Sixty-six patients, including eight lung transplant patients, underwent a total of 112 endoscopic sinus surgery procedures; 25 patients underwent more than one procedure. Patients were taking oral steroids preoperatively in 28{\%} of procedures and inhaled steroids in 40{\%}. Postoperatively, there was no statistically significant change in oral or inhaled steroid use, or in postoperative pulmonary function. If the index hospitalization, which was often for reasons not related to sinus disease, was considered part of the preoperative time period, endoscopic sinus surgery (ESS) was noted to result in a marked reduction (9.5 days (adjusted), P=0.001) in hospital days during the subsequent 6 months. If the date of the procedure alone was used to define pre- and postoperative time periods, the reduction in postoperative days was more modest and not statistically significant (3.5 days (adjusted), P=0.21). Conclusions: Although we found no statistically significant difference in PFTs, or steroid requirements following ESS, ESS may have resulted in a reduced need for hospitalization in the 6 months following the procedure. Future prospective studies in a larger number of patients and using more detailed outcome measures are needed to better evaluate the effects of endoscopic sinus surgery in pediatric patients with CF.",
keywords = "Cystic fibrosis, Endoscopic sinus surgery",
author = "Rosbe, {Kristina W.} and Jones, {Dwight T.} and Reza Rahbar and Thomas Lahiri and Auerbach, {Andrew D.}",
year = "2001",
month = "11",
day = "1",
doi = "10.1016/S0165-5876(01)00556-0",
language = "English (US)",
volume = "61",
pages = "113--119",
journal = "International Journal of Pediatric Otorhinolaryngology",
issn = "0165-5876",
publisher = "Elsevier Ireland Ltd",
number = "2",

}

TY - JOUR

T1 - Endoscopic sinus surgery in cystic fibrosis

T2 - Do patients benefit from surgery?

AU - Rosbe, Kristina W.

AU - Jones, Dwight T.

AU - Rahbar, Reza

AU - Lahiri, Thomas

AU - Auerbach, Andrew D.

PY - 2001/11/1

Y1 - 2001/11/1

N2 - Objective: To examine the effects of endoscopic sinus surgery on the pulmonary status of cystic fibrosis (CF) patients through the objective parameters of steroid use, pulmonary function tests (PFTs), and inpatient hospital days (IHDs). Methods: Retrospective chart review of all patients with CF who underwent endoscopic sinus surgery from 1993 to 1999 at a tertiary care children's hospital. Preoperative pulmonary function, inhaler and steroid use, and IHDs were compared to postoperative parameters within a 1-year period. Results: Sixty-six patients, including eight lung transplant patients, underwent a total of 112 endoscopic sinus surgery procedures; 25 patients underwent more than one procedure. Patients were taking oral steroids preoperatively in 28% of procedures and inhaled steroids in 40%. Postoperatively, there was no statistically significant change in oral or inhaled steroid use, or in postoperative pulmonary function. If the index hospitalization, which was often for reasons not related to sinus disease, was considered part of the preoperative time period, endoscopic sinus surgery (ESS) was noted to result in a marked reduction (9.5 days (adjusted), P=0.001) in hospital days during the subsequent 6 months. If the date of the procedure alone was used to define pre- and postoperative time periods, the reduction in postoperative days was more modest and not statistically significant (3.5 days (adjusted), P=0.21). Conclusions: Although we found no statistically significant difference in PFTs, or steroid requirements following ESS, ESS may have resulted in a reduced need for hospitalization in the 6 months following the procedure. Future prospective studies in a larger number of patients and using more detailed outcome measures are needed to better evaluate the effects of endoscopic sinus surgery in pediatric patients with CF.

AB - Objective: To examine the effects of endoscopic sinus surgery on the pulmonary status of cystic fibrosis (CF) patients through the objective parameters of steroid use, pulmonary function tests (PFTs), and inpatient hospital days (IHDs). Methods: Retrospective chart review of all patients with CF who underwent endoscopic sinus surgery from 1993 to 1999 at a tertiary care children's hospital. Preoperative pulmonary function, inhaler and steroid use, and IHDs were compared to postoperative parameters within a 1-year period. Results: Sixty-six patients, including eight lung transplant patients, underwent a total of 112 endoscopic sinus surgery procedures; 25 patients underwent more than one procedure. Patients were taking oral steroids preoperatively in 28% of procedures and inhaled steroids in 40%. Postoperatively, there was no statistically significant change in oral or inhaled steroid use, or in postoperative pulmonary function. If the index hospitalization, which was often for reasons not related to sinus disease, was considered part of the preoperative time period, endoscopic sinus surgery (ESS) was noted to result in a marked reduction (9.5 days (adjusted), P=0.001) in hospital days during the subsequent 6 months. If the date of the procedure alone was used to define pre- and postoperative time periods, the reduction in postoperative days was more modest and not statistically significant (3.5 days (adjusted), P=0.21). Conclusions: Although we found no statistically significant difference in PFTs, or steroid requirements following ESS, ESS may have resulted in a reduced need for hospitalization in the 6 months following the procedure. Future prospective studies in a larger number of patients and using more detailed outcome measures are needed to better evaluate the effects of endoscopic sinus surgery in pediatric patients with CF.

KW - Cystic fibrosis

KW - Endoscopic sinus surgery

UR - http://www.scopus.com/inward/record.url?scp=0035501687&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035501687&partnerID=8YFLogxK

U2 - 10.1016/S0165-5876(01)00556-0

DO - 10.1016/S0165-5876(01)00556-0

M3 - Article

C2 - 11589977

AN - SCOPUS:0035501687

VL - 61

SP - 113

EP - 119

JO - International Journal of Pediatric Otorhinolaryngology

JF - International Journal of Pediatric Otorhinolaryngology

SN - 0165-5876

IS - 2

ER -