Endocannabinoids, metabolic regulation, and the role of diet

Timothy P. Carr, Elliot D. Jesch, Andrew W. Brown

Research output: Contribution to journalReview article

27 Citations (Scopus)

Abstract

Understanding the endocannabinoid system as it relates to health and disease is a relatively new area of study. The discovery and cloning of cannabinoid receptors have prompted an increase in research aimed at identifying endogenous ligands ("endocannabinoids") and how these receptors and ligands regulate a variety of physiologic and pathologic events that include bone formation, the cardiovascular system, appetite control, and energy metabolism. With regard to nutrition, researchers have begun to ask whether the known effects of diet on metabolic processes are mediated through endocannabinoids and their receptors. Although only a few studies have been conducted that directly address the role of diet, results indicate that endocannabinoids can be regulated by eating frequency and by specific dietary components, particularly fatty acids. This review provides an overview of the endocannabinoid system and its control of metabolism, with emphasis on the impact of diet.

Original languageEnglish (US)
Pages (from-to)641-650
Number of pages10
JournalNutrition Research
Volume28
Issue number10
DOIs
StatePublished - Oct 1 2008

Fingerprint

Endocannabinoids
Diet
Ligands
Cannabinoid Receptors
Appetite
Cardiovascular System
Osteogenesis
Energy Metabolism
Organism Cloning
Fatty Acids
Eating
Research Personnel
Health
Research

Keywords

  • Bone
  • Cardiovascular
  • Dietary fats
  • Endocannabinoid receptors
  • Endocannabinoids
  • Energy metabolism
  • Metabolic regulation
  • Review

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Nutrition and Dietetics

Cite this

Endocannabinoids, metabolic regulation, and the role of diet. / Carr, Timothy P.; Jesch, Elliot D.; Brown, Andrew W.

In: Nutrition Research, Vol. 28, No. 10, 01.10.2008, p. 641-650.

Research output: Contribution to journalReview article

Carr, Timothy P. ; Jesch, Elliot D. ; Brown, Andrew W. / Endocannabinoids, metabolic regulation, and the role of diet. In: Nutrition Research. 2008 ; Vol. 28, No. 10. pp. 641-650.
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