Endarterectomy and stenting for asymptomatic carotid stenosis: A race at breakneck speed

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Atherosclerotic carotid stenosis has been recognized for the past several decades as being responsible for a significant portion of ischemic stroke, particularly the major and disabling ones. This category of stroke distinguished itself as being one of the first ones to have an effective preventive treatment in carotid endarterectomy. It took over 4 decades before major randomized, controlled trials were completed in North America and Europe to provide enough definitive information about its effectiveness, risks, limitations, and categories of patients that most benefit from it. Just like any invasive surgery, endarterectomy is being challenged by minimally invasive stenting, which has already made major technologic leaps and rapid clinical inroads. Stenting has started by tackling patient populations like surgical high-risk patients who were largely avoided in the endarterectomy trials and demonstrated equivalence to it in such populations. The broader applicability of the technique, however, has not been yet adequately investigated. The results so far are greatly reassuring and encouraging to enroll patients in the ongoing randomized trials that will hopefully provide more definitive answers to this issue.

Original languageEnglish (US)
Pages (from-to)707-714
Number of pages8
JournalStroke
Volume38
Issue number2 PART 2
DOIs
StatePublished - Feb 1 2007

Fingerprint

Endarterectomy
Carotid Stenosis
Stroke
Carotid Endarterectomy
North America
Population
Randomized Controlled Trials
Therapeutics

Keywords

  • Angioplasty and stenting
  • Asymptomatic carotid stenosis
  • Carotid endarterectomy
  • Carotid stenosis
  • Prevention

ASJC Scopus subject areas

  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine
  • Advanced and Specialized Nursing

Cite this

Endarterectomy and stenting for asymptomatic carotid stenosis : A race at breakneck speed. / Fayad, Pierre B.

In: Stroke, Vol. 38, No. 2 PART 2, 01.02.2007, p. 707-714.

Research output: Contribution to journalArticle

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