Electrospinning of chitosan derivative nanofibers with structural stability in an aqueous environment

Ashleigh Cooper, Narayan Bhattarai, Forrest M. Kievit, Michael Rossol, Miqin Zhang

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

We report a simple method to produce stable chitosan derivative nanofibers via electrospinning. A chitosan solution with lactate salt was electrospun to produce nanofibers, followed by thermal treatment to enhance fiber stability. Chemical and morphological analyses demonstrated that the resulting nanofibers were crosslinked via amidation between chitosan and lactate salt. These fibers exhibited sustained morphological and structural stabilities to serve as a scaffold for biomedical applications.

Original languageEnglish (US)
Pages (from-to)9969-9972
Number of pages4
JournalPhysical Chemistry Chemical Physics
Volume13
Issue number21
DOIs
StatePublished - Jun 7 2011

Fingerprint

lactates
Chitosan
structural stability
Electrospinning
Nanofibers
salts
Derivatives
fibers
Lactic Acid
Salts
Fibers
Scaffolds
Heat treatment

ASJC Scopus subject areas

  • Physics and Astronomy(all)
  • Physical and Theoretical Chemistry

Cite this

Electrospinning of chitosan derivative nanofibers with structural stability in an aqueous environment. / Cooper, Ashleigh; Bhattarai, Narayan; Kievit, Forrest M.; Rossol, Michael; Zhang, Miqin.

In: Physical Chemistry Chemical Physics, Vol. 13, No. 21, 07.06.2011, p. 9969-9972.

Research output: Contribution to journalArticle

Cooper, Ashleigh ; Bhattarai, Narayan ; Kievit, Forrest M. ; Rossol, Michael ; Zhang, Miqin. / Electrospinning of chitosan derivative nanofibers with structural stability in an aqueous environment. In: Physical Chemistry Chemical Physics. 2011 ; Vol. 13, No. 21. pp. 9969-9972.
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