Effects of twenty-eight days of beta-alanine and creatine monohydrate supplementation on the physical working capacity at neuromuscular fatigue threshold

Jeffrey R. Stout, Joel T Cramer, Michelle Mielke, Joseph O'Kroy, Don J. Torok, Robert F. Zoeller

Research output: Contribution to journalArticle

76 Citations (Scopus)

Abstract

The purpose of this study was to examine the effects of 28 days of beta-alanine (b-Ala) and creatine monohydrate (CrM) supplementation on the onset of neuromuscular fatigue by using the physical working capacity at neuromuscular fatigue threshold (PWCFT) test in untrained men. Fifty-one men (mean age ± SD = 24.5 ± 5.3 years) volunteered to participate in this 28-day, double-blind, placebo-controlled study and were randomly assigned to 1 of 4 groups: placebo (PLA; 34 g dextrose; n = 13), CrM (5.25 g CrM plus 34 g dextrose; n = 12), b-Ala (1.6 g b-Ala plus 34 g of dextrose; n = 12), or b-Ala plus CrM (CrBA; 5.25 g CrM plus 1.6 g b-Ala plus 34 g dextrose; n = 14). The supplement was ingested 4 times per day for 6 consecutive days, then twice per day for 22 days before posttesting. Before and after the supplementation, subjects performed a continuous incremental cycle ergometry test while a surface electromyographic signal was recorded from the vastus lateralis muscle to determine PWCFT. The adjusted mean posttest PWCFT values (covaried for pretest PWCFT values) for the b-Ala and CrBA groups were greater than those for the PLA group (p ≤ 0.05). However, there were no differences between the CrM vs. PLA, CrBA vs. b-Ala, CrM vs. b-Ala, or CrM vs. CrBA groups (p > 0.05). These findings suggested that b-Ala supplementation may delay the onset of neuromuscular fatigue. Furthermore, there appeared to be no additive or unique effects of CrM vs. b-Ala alone on PWCFT.

Original languageEnglish (US)
Pages (from-to)928-931
Number of pages4
JournalJournal of strength and conditioning research
Volume20
Issue number4
DOIs
StatePublished - Nov 1 2006

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beta-Alanine
Creatine
Fatigue
Glucose
Placebos
Ergometry
Quadriceps Muscle

Keywords

  • Carnosine
  • Cycle ergometry
  • Electromyography
  • Ergogenic aids

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Effects of twenty-eight days of beta-alanine and creatine monohydrate supplementation on the physical working capacity at neuromuscular fatigue threshold. / Stout, Jeffrey R.; Cramer, Joel T; Mielke, Michelle; O'Kroy, Joseph; Torok, Don J.; Zoeller, Robert F.

In: Journal of strength and conditioning research, Vol. 20, No. 4, 01.11.2006, p. 928-931.

Research output: Contribution to journalArticle

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