Effects of age, gender and hemispheric location on T2 hypointensity in the Pulvinar at 3T

Matthew L White, Yan Zhang, Jason T. Helvey, Fang Yu, Matthew F. Omojola

Research output: Contribution to journalReview article

Abstract

Pulvinar signal intensity decrease on T2-weighted images has been reported in some neurological abnormalities. We aimed to define the normal T2 signal hypointensity pattern present in the pulvinar to avoid erroneous radiological interpretation. One hundred and forty-two subjects (54 men and 88 women; age range 9-91 years) with unremarkable brain 3T MR findings were enrolled. MR images were analyzed with regard to signal intensity of the pulvinar relative to the thalamus on fluid attenuated inversion recovery images. Effects of age, gender and hemispheric location on the degree of T2 hypointensity were statistically analyzed. The statistical association was measured between the pattern of signal changes in the pulvinar region and that in the putamen and the globus pallidus. We detected a linear signal decrease in the pulvinar region with age. The male subjects had a more rapid decrease of signal with age than female subjects. The right pulvinar region had a higher chance of hypointensity compared to the left. A positive linear association was found when signal change from the pulvinar region was compared with signal in the putamen and globus pallidus. We detected a linear signal decrease with age in the pulvinar. The physiological signal features of the pulvinar also depend on gender and hemispheric lateralization. The pattern of signal change in the pulvinar is similar to but not the same as that in the putamen and globus pallidus.

Original languageEnglish (US)
Pages (from-to)645-652
Number of pages8
JournalNeuroradiology Journal
Volume27
Issue number6
DOIs
StatePublished - Dec 1 2014

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Pulvinar
Globus Pallidus
Putamen
Thalamus

Keywords

  • MR imaging
  • Pulvinar
  • T2 hypointensity

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

Cite this

Effects of age, gender and hemispheric location on T2 hypointensity in the Pulvinar at 3T. / White, Matthew L; Zhang, Yan; Helvey, Jason T.; Yu, Fang; Omojola, Matthew F.

In: Neuroradiology Journal, Vol. 27, No. 6, 01.12.2014, p. 645-652.

Research output: Contribution to journalReview article

White, Matthew L ; Zhang, Yan ; Helvey, Jason T. ; Yu, Fang ; Omojola, Matthew F. / Effects of age, gender and hemispheric location on T2 hypointensity in the Pulvinar at 3T. In: Neuroradiology Journal. 2014 ; Vol. 27, No. 6. pp. 645-652.
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