Effects of 4 ipomeanol, a product from mold damaged sweet potatoes, on the bovine lung

A. R. Doster, F. E. Mitchell, R. L. Farrell, B. J. Wilson

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Cattle given intraruminal administration of 4-ipomeanol, a furanoterpenoid originally obtained from sweet potatoes infected with Fusarium solani (F. javanicum), developed a respiratory syndrome clinically and histologically indistinguishable from atypical interstitial pneumonia. There were edema and emphysema in the lungs and mediastinum. The maximum nonlethal oral dose of 4-ipomeanol was estimated to be between 7.5 and 9 mg/kg of body weight.

Original languageEnglish (US)
Pages (from-to)367-375
Number of pages9
JournalVeterinary pathology
Volume15
Issue number3
DOIs
StatePublished - Jan 1 1978

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intraruminal administration
mediastinum
Ipomoea batatas
Fusarium solani
sweet potatoes
edema
pneumonia
mouth
Fungi
lungs
Lung
body weight
cattle
Interstitial Lung Diseases
Emphysema
Fusarium
Mediastinum
dosage
Edema
Body Weight

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Effects of 4 ipomeanol, a product from mold damaged sweet potatoes, on the bovine lung. / Doster, A. R.; Mitchell, F. E.; Farrell, R. L.; Wilson, B. J.

In: Veterinary pathology, Vol. 15, No. 3, 01.01.1978, p. 367-375.

Research output: Contribution to journalArticle

Doster, A. R. ; Mitchell, F. E. ; Farrell, R. L. ; Wilson, B. J. / Effects of 4 ipomeanol, a product from mold damaged sweet potatoes, on the bovine lung. In: Veterinary pathology. 1978 ; Vol. 15, No. 3. pp. 367-375.
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