Effect of narcotic pain reliever on pulp tests in women

Anthony C. Kardelis, Trudy A. Meinberg, Heather R. Sulte, Tom G. Gound, David B. Marx, Richard A Reinhardt

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

The purpose of this study was to determine the effect of one dose of a common narcotic-based pain reliever (Vicodin) on a battery of oral sensitivity tests across time in women. Fifteen Caucasian women randomly were given an oral dose of 10 mg of hydrocodone/1000 mg of acetaminophen or placebo in a double-blind, cross-over design. At baseline (before drug) and after 2, 4, and 8 h each subject was evaluated for sensitivity thresholds with four tests around an experimental tooth: (a) electric pulp tester applied to exposed root; (b) electric pulp tester on adjacent mucosa; (c) increasing probe pressure (grams) on adjacent mucosa; and (d) decreasing cold probe (°C) on the exposed root. The outcomes of all tests were not statistically different between drug and placebo treatments at any time point (p > 0.05). These results suggest that a systemic dose of hydrocodone/ acetaminophen has little impact on healthy pulp or mucosa sensitivity in women as measured by common diagnostic tests.

Original languageEnglish (US)
Pages (from-to)537-539
Number of pages3
JournalJournal of Endodontics
Volume28
Issue number7
DOIs
StatePublished - Jan 1 2002

Fingerprint

Narcotics
Mucous Membrane
Pain
Hydrocodone
Placebos
Acetaminophen
Routine Diagnostic Tests
Pharmaceutical Preparations
Cross-Over Studies
Tooth
Pressure
hydrocodone drug combination acetaminophen
Therapeutics

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Kardelis, A. C., Meinberg, T. A., Sulte, H. R., Gound, T. G., Marx, D. B., & Reinhardt, R. A. (2002). Effect of narcotic pain reliever on pulp tests in women. Journal of Endodontics, 28(7), 537-539. https://doi.org/10.1097/00004770-200207000-00013

Effect of narcotic pain reliever on pulp tests in women. / Kardelis, Anthony C.; Meinberg, Trudy A.; Sulte, Heather R.; Gound, Tom G.; Marx, David B.; Reinhardt, Richard A.

In: Journal of Endodontics, Vol. 28, No. 7, 01.01.2002, p. 537-539.

Research output: Contribution to journalArticle

Kardelis, AC, Meinberg, TA, Sulte, HR, Gound, TG, Marx, DB & Reinhardt, RA 2002, 'Effect of narcotic pain reliever on pulp tests in women', Journal of Endodontics, vol. 28, no. 7, pp. 537-539. https://doi.org/10.1097/00004770-200207000-00013
Kardelis, Anthony C. ; Meinberg, Trudy A. ; Sulte, Heather R. ; Gound, Tom G. ; Marx, David B. ; Reinhardt, Richard A. / Effect of narcotic pain reliever on pulp tests in women. In: Journal of Endodontics. 2002 ; Vol. 28, No. 7. pp. 537-539.
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