Effect of biotin limitation on the conversion of xylose to ethanol and xylitol by Pachysolen tannophilus and Candida guilliermondii

Hung Lee, Audrey L. Atkin, Maria F.S. Barbosa, Delbert R. Dorscheid, Henry Schneider

Research output: Contribution to journalArticle

34 Scopus citations


The relative amount of ethanol and xylitol accumulated in aerobic batch cultures of Pachysolen tannophilus and Candida guilliermondii on d-xylose depended on the extent of limitation by biotin. In high biotin media P. tannophilus favored ethanol production over that of xylitol while C. guilliermondii favored xylitol formation. However, as the extent of biotin limitation increased, the ratio of ethanol to xylitol produced by both organisms increased. The results are of interest in efforts to control such ratios.

Original languageEnglish (US)
Pages (from-to)81-84
Number of pages4
JournalEnzyme and Microbial Technology
Issue number2
StatePublished - Feb 1988



  • Candida guilliermondii
  • Growth
  • Pachysolen tannophilus
  • biotin
  • d-xylose
  • ethanol
  • limitation
  • xylitol
  • yeast

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biochemistry
  • Applied Microbiology and Biotechnology

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