Effect of an anti-oestrogen on implantation of mouse blastocysts

J. Sengupta, Shyamal K Roy, S. K. Manchanda

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Mouse blastocysts collected on Day 4 were cultured for 4 h in Whitten's medium containing in 5 μg CI-628 citrate, a specific estrogen antagonist, and transferred to the uteri of pseudopregnant hosts. There was a significant reduction in the number of implantations observed on Day 11 when compared with those from blastocysts which were similarly transferred after culture in medium alone or in medium containing 1 μg estradiol 17β and 5 μg CI-628 citrate. We suggest that this is further evidence for the involvement of embryonic estrogen in implantation.

Original languageEnglish (US)
Pages (from-to)433-436
Number of pages4
JournalJournal of reproduction and fertility
Volume62
Issue number2
DOIs
StatePublished - Jan 1 1981

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Nitromifene
Blastocyst
Citric Acid
Estrogens
Estrogen Antagonists
Uterus
Culture Media
Estradiol

ASJC Scopus subject areas

  • Physiology
  • Embryology
  • Molecular Biology
  • Obstetrics and Gynecology
  • Developmental Biology

Cite this

Effect of an anti-oestrogen on implantation of mouse blastocysts. / Sengupta, J.; Roy, Shyamal K; Manchanda, S. K.

In: Journal of reproduction and fertility, Vol. 62, No. 2, 01.01.1981, p. 433-436.

Research output: Contribution to journalArticle

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