Effect of accessory pulmonary blood flow on survival after the bidirectional Glenn procedure

Richard D. Mainwaring, John J. Lamberti, Karen Uzark, Robert L Spicer, Mark W. Cocalis, John W. Moore

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

Background - The bidirectional Glenn procedure (BDG) is used in the staged surgical management of patients with a functional single ventricle. Controversy exists regarding whether accessory pulmonary blood flow (APBF) should be left at the time of BDG to augment systemic saturation or be eliminated to reduce volume load of the ventricle. The present study was a retrospective review of patients undergoing BDG that was conducted to assess the influence of APBF on survival rates. Methods and Results - From 1986 through 1998, 149 patients have undergone BDG at our institution. Ninety- three patients had elimination of all sources of APBF, whereas 56 patients had either a shunt or a patent right ventricular outflow tract intentionally left in place to augment the pulmonary blood flow provided by the BDG. The operative mortality rate was 2.2% without APBF and 5.4% with APBF. The late mortality rate was 4.4% without APBF and 15.1% with APBF. Actuarial analysis demonstrates a divergence of the Kaplan-Meier curves ill favor of patients in whom APBF was eliminated (P<0.02). One hundred seven patients have subsequently undergone completion of their Fontan operation, so the actuarial analysis includes the operative risk of this second operation. Conclusions - The results suggest that the elimination of APBF at the time of BDG may confer a long-term advantage for patients with a functional single ventricle.

Original languageEnglish (US)
JournalCirculation
Volume100
Issue number19 SUPPL.
StatePublished - Nov 9 1999

Fingerprint

Fontan Procedure
Lung
Survival
Actuarial Analysis
Mortality
Survival Rate

Keywords

  • Blood flow
  • Fontan procedure
  • Morbidity
  • Mortality

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

Cite this

Mainwaring, R. D., Lamberti, J. J., Uzark, K., Spicer, R. L., Cocalis, M. W., & Moore, J. W. (1999). Effect of accessory pulmonary blood flow on survival after the bidirectional Glenn procedure. Circulation, 100(19 SUPPL.).

Effect of accessory pulmonary blood flow on survival after the bidirectional Glenn procedure. / Mainwaring, Richard D.; Lamberti, John J.; Uzark, Karen; Spicer, Robert L; Cocalis, Mark W.; Moore, John W.

In: Circulation, Vol. 100, No. 19 SUPPL., 09.11.1999.

Research output: Contribution to journalArticle

Mainwaring, RD, Lamberti, JJ, Uzark, K, Spicer, RL, Cocalis, MW & Moore, JW 1999, 'Effect of accessory pulmonary blood flow on survival after the bidirectional Glenn procedure', Circulation, vol. 100, no. 19 SUPPL..
Mainwaring RD, Lamberti JJ, Uzark K, Spicer RL, Cocalis MW, Moore JW. Effect of accessory pulmonary blood flow on survival after the bidirectional Glenn procedure. Circulation. 1999 Nov 9;100(19 SUPPL.).
Mainwaring, Richard D. ; Lamberti, John J. ; Uzark, Karen ; Spicer, Robert L ; Cocalis, Mark W. ; Moore, John W. / Effect of accessory pulmonary blood flow on survival after the bidirectional Glenn procedure. In: Circulation. 1999 ; Vol. 100, No. 19 SUPPL.
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