Doping-control urinalysis of a ginseng extract, Cold-FX®, in athletes

Danny P. Goel, Jonathan Geiger, Jacqueline J. Shan, Dean Kriellaars, Grant N. Pierce

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Nutraceuticals may induce doping infractions through contamination of the product itself or their ingestion might be metabolized within the body to create a positive doping control test. We tested this possibility using a commercially available, proprietary ginseng root extract (Cold-FX®, CV Technologies Inc., Edmonton, AB). After athletes ingested Cold-FX® for 28 d at 400 mg/d, urine samples were collected and processed under strict IOC doping control guidelines and then analyzed for a full screen of IOC banned/restricted substances by an IOC-approved laboratory. There were no positive tests for any banned substances in any of the subjects. Our study demonstrates that ingestion of Cold-FX® for 28 d at 400 mg/d does not represent a doping concern for athletes. Carefully controlled clinical studies like this one are necessary to provide the athlete, the nutraceutical industry and IOC regulatory bodies with information to avoid inadvertent exposure to banned/restricted or potentially unhealthy substances.

Original languageEnglish (US)
Pages (from-to)473-480
Number of pages8
JournalInternational Journal of Sport Nutrition and Exercise Metabolism
Volume14
Issue number4
DOIs
StatePublished - Jan 1 2004

Fingerprint

Panax
Urinalysis
Athletes
Dietary Supplements
Eating
Industry
Urine
Guidelines
Technology

Keywords

  • Athletic performance
  • Dietary supplements
  • Health foods
  • Natural health products
  • Nutraceuticals

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Orthopedics and Sports Medicine
  • Nutrition and Dietetics

Cite this

Doping-control urinalysis of a ginseng extract, Cold-FX®, in athletes. / Goel, Danny P.; Geiger, Jonathan; Shan, Jacqueline J.; Kriellaars, Dean; Pierce, Grant N.

In: International Journal of Sport Nutrition and Exercise Metabolism, Vol. 14, No. 4, 01.01.2004, p. 473-480.

Research output: Contribution to journalArticle

Goel, Danny P. ; Geiger, Jonathan ; Shan, Jacqueline J. ; Kriellaars, Dean ; Pierce, Grant N. / Doping-control urinalysis of a ginseng extract, Cold-FX®, in athletes. In: International Journal of Sport Nutrition and Exercise Metabolism. 2004 ; Vol. 14, No. 4. pp. 473-480.
@article{3f24bceba6bd4bc99f2ebd816b705ae5,
title = "Doping-control urinalysis of a ginseng extract, Cold-FX{\circledR}, in athletes",
abstract = "Nutraceuticals may induce doping infractions through contamination of the product itself or their ingestion might be metabolized within the body to create a positive doping control test. We tested this possibility using a commercially available, proprietary ginseng root extract (Cold-FX{\circledR}, CV Technologies Inc., Edmonton, AB). After athletes ingested Cold-FX{\circledR} for 28 d at 400 mg/d, urine samples were collected and processed under strict IOC doping control guidelines and then analyzed for a full screen of IOC banned/restricted substances by an IOC-approved laboratory. There were no positive tests for any banned substances in any of the subjects. Our study demonstrates that ingestion of Cold-FX{\circledR} for 28 d at 400 mg/d does not represent a doping concern for athletes. Carefully controlled clinical studies like this one are necessary to provide the athlete, the nutraceutical industry and IOC regulatory bodies with information to avoid inadvertent exposure to banned/restricted or potentially unhealthy substances.",
keywords = "Athletic performance, Dietary supplements, Health foods, Natural health products, Nutraceuticals",
author = "Goel, {Danny P.} and Jonathan Geiger and Shan, {Jacqueline J.} and Dean Kriellaars and Pierce, {Grant N.}",
year = "2004",
month = "1",
day = "1",
doi = "10.1123/ijsnem.14.4.473",
language = "English (US)",
volume = "14",
pages = "473--480",
journal = "International Journal of Sport Nutrition and Exercise Metabolism",
issn = "1526-484X",
publisher = "Human Kinetics Publishers Inc.",
number = "4",

}

TY - JOUR

T1 - Doping-control urinalysis of a ginseng extract, Cold-FX®, in athletes

AU - Goel, Danny P.

AU - Geiger, Jonathan

AU - Shan, Jacqueline J.

AU - Kriellaars, Dean

AU - Pierce, Grant N.

PY - 2004/1/1

Y1 - 2004/1/1

N2 - Nutraceuticals may induce doping infractions through contamination of the product itself or their ingestion might be metabolized within the body to create a positive doping control test. We tested this possibility using a commercially available, proprietary ginseng root extract (Cold-FX®, CV Technologies Inc., Edmonton, AB). After athletes ingested Cold-FX® for 28 d at 400 mg/d, urine samples were collected and processed under strict IOC doping control guidelines and then analyzed for a full screen of IOC banned/restricted substances by an IOC-approved laboratory. There were no positive tests for any banned substances in any of the subjects. Our study demonstrates that ingestion of Cold-FX® for 28 d at 400 mg/d does not represent a doping concern for athletes. Carefully controlled clinical studies like this one are necessary to provide the athlete, the nutraceutical industry and IOC regulatory bodies with information to avoid inadvertent exposure to banned/restricted or potentially unhealthy substances.

AB - Nutraceuticals may induce doping infractions through contamination of the product itself or their ingestion might be metabolized within the body to create a positive doping control test. We tested this possibility using a commercially available, proprietary ginseng root extract (Cold-FX®, CV Technologies Inc., Edmonton, AB). After athletes ingested Cold-FX® for 28 d at 400 mg/d, urine samples were collected and processed under strict IOC doping control guidelines and then analyzed for a full screen of IOC banned/restricted substances by an IOC-approved laboratory. There were no positive tests for any banned substances in any of the subjects. Our study demonstrates that ingestion of Cold-FX® for 28 d at 400 mg/d does not represent a doping concern for athletes. Carefully controlled clinical studies like this one are necessary to provide the athlete, the nutraceutical industry and IOC regulatory bodies with information to avoid inadvertent exposure to banned/restricted or potentially unhealthy substances.

KW - Athletic performance

KW - Dietary supplements

KW - Health foods

KW - Natural health products

KW - Nutraceuticals

UR - http://www.scopus.com/inward/record.url?scp=4344601007&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=4344601007&partnerID=8YFLogxK

U2 - 10.1123/ijsnem.14.4.473

DO - 10.1123/ijsnem.14.4.473

M3 - Article

VL - 14

SP - 473

EP - 480

JO - International Journal of Sport Nutrition and Exercise Metabolism

JF - International Journal of Sport Nutrition and Exercise Metabolism

SN - 1526-484X

IS - 4

ER -