Abstract

Giant cell arteritis (GCA) is well known for its involvement of the proximal aorta and its branches, classically causing headache, visual impairment, and elevations in the erythrocyte sedimentation rate (ESR) or C-reactive protein (CRP). We describe a case of biopsy-proven GCA initially presenting with limb claudication, oligoarticular inflammatory arthritis, and a positive antineutrophil cytoplasmic antibody with cytoplasmic staining (C-ANCA), treated successfully with a combination of prednisone and weekly methotrexate. This case illustrates the wide spectrum of features that can be seen with GCA, including the occasional presence of C-ANCA. The C-ANCA became negative after treatment.

Original languageEnglish (US)
Pages (from-to)216-218
Number of pages3
JournalJournal of Clinical Rheumatology
Volume11
Issue number4
DOIs
StatePublished - Aug 1 2005

Fingerprint

Giant Cell Arteritis
Arthritis
Staining and Labeling
Antibodies
Negative Staining
Antineutrophil Cytoplasmic Antibodies
Blood Sedimentation
Vision Disorders
Prednisone
Methotrexate
C-Reactive Protein
Headache
Aorta
Extremities
Biopsy
Therapeutics

Keywords

  • Antineutrophil cytoplasm antibodies
  • Claudication
  • Giant cell arteritis
  • Inflammatory arthritis

ASJC Scopus subject areas

  • Rheumatology

Cite this

Disseminated giant cell arteritis with inflammatory arthritis and C-ANCA. / Snow, Marcus H; Radio, Stanley J; Mikuls, Ted R.

In: Journal of Clinical Rheumatology, Vol. 11, No. 4, 01.08.2005, p. 216-218.

Research output: Contribution to journalArticle

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