Diagnosing Pulmonary Embolism Using Clinical Findings

V. L. Hoellerich, Robert Swift Wigton

Research output: Contribution to journalArticle

84 Scopus citations

Abstract

• To determine the value of clinical findings in the diagnosis of pulmonary embolism, we analyzed the records of 82 patients from three different hospitals who underwent pulmonary arteriography to rule out pulmonary embolism. We recorded 92 items of clinical information, including lung ventilation-perfusion scan results, for each patient. Although the diagnostic power of any single variable was marginal, an eight-item decision rule derived using discriminant analysis correctly predicted the outcome of arteriography in 82% of the cases. When tested on a different group of 68 patients from four hospitals, the rule accurately identified patients with low or high likelihood of having positive arteriograms. Clinical use of such a rule could reduce the need for arteriography in this population and would expedite decisions about anticoagulant therapy and further diagnostic testing.

Original languageEnglish (US)
Pages (from-to)1699-1704
Number of pages6
JournalArchives of Internal Medicine
Volume146
Issue number9
DOIs
Publication statusPublished - Sep 1986

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ASJC Scopus subject areas

  • Internal Medicine

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