Developmental orofacial deficits associated with multimodal cancer therapy

case report.

R. J. Berkowitz, P. Neuman, P. Spalding, L. Novak, S. Strandjord, Peter Felix Coccia

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Multimodal cancer therapy for pediatric head and neck tumors may be associated with significant developmental orofacial morbidity. This report details these effects in a child (C.I.) diagnosed at 2.5 years of age with a rhabdomyosarcoma, primary to the left buccinator. This case is of interest as C.I. has an unaffected identical twin (D.I.) for comparative study. Both were assessed by comparing panoramic radiographs and lateral and frontal tracings of cephalometric radiographs obtained at 8.25 years of age. C.I. had multiple dental anomalies which included agenesis, ectopia, crown malformation, and root malformation. Root malformation, ectopia, and agenesis were restricted to the left dentition, whereas crown malformation was noted bilaterally. C.I. had a generalized craniofacial skeletal hypoplasia relative to D.I. in all three planes, growth defects were greater on the side of the tumor, and the mandible was affected more than the nasomaxillary complex.

Original languageEnglish (US)
Pages (from-to)227-231
Number of pages5
JournalPediatric dentistry
Volume11
Issue number3
StatePublished - Sep 1 1989

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Crowns
Neoplasms
Cephalometry
Dentition
Monozygotic Twins
Rhabdomyosarcoma
Therapeutics
Mandible
Tooth
Neck
Head
Pediatrics
Morbidity
Growth

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Berkowitz, R. J., Neuman, P., Spalding, P., Novak, L., Strandjord, S., & Coccia, P. F. (1989). Developmental orofacial deficits associated with multimodal cancer therapy: case report. Pediatric dentistry, 11(3), 227-231.

Developmental orofacial deficits associated with multimodal cancer therapy : case report. / Berkowitz, R. J.; Neuman, P.; Spalding, P.; Novak, L.; Strandjord, S.; Coccia, Peter Felix.

In: Pediatric dentistry, Vol. 11, No. 3, 01.09.1989, p. 227-231.

Research output: Contribution to journalArticle

Berkowitz, RJ, Neuman, P, Spalding, P, Novak, L, Strandjord, S & Coccia, PF 1989, 'Developmental orofacial deficits associated with multimodal cancer therapy: case report.', Pediatric dentistry, vol. 11, no. 3, pp. 227-231.
Berkowitz RJ, Neuman P, Spalding P, Novak L, Strandjord S, Coccia PF. Developmental orofacial deficits associated with multimodal cancer therapy: case report. Pediatric dentistry. 1989 Sep 1;11(3):227-231.
Berkowitz, R. J. ; Neuman, P. ; Spalding, P. ; Novak, L. ; Strandjord, S. ; Coccia, Peter Felix. / Developmental orofacial deficits associated with multimodal cancer therapy : case report. In: Pediatric dentistry. 1989 ; Vol. 11, No. 3. pp. 227-231.
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