Development of a "signal-on" electrochemical DNA sensor with an oligo-thymine spacer for point mutation detection

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

We report a reagentless and reusable "signal-on" electrochemical DNA sensor that utilizes oligo-thymine as a flexible spacer. This sensor design is sensitive, specific, and selective; it is potentially generalizable for detection of a wide range of biomedical-relevant nucleic acid sequences.

Original languageEnglish (US)
Pages (from-to)3422-3424
Number of pages3
JournalChemical Communications
Volume49
Issue number33
DOIs
StatePublished - Apr 28 2013

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Thymine
DNA
Nucleic acid sequences
Sensors

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

Development of a "signal-on" electrochemical DNA sensor with an oligo-thymine spacer for point mutation detection. / Wu, Yao; Lai, Rebecca Y.

In: Chemical Communications, Vol. 49, No. 33, 28.04.2013, p. 3422-3424.

Research output: Contribution to journalArticle

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