Detection of measles virus RNA in urine specimens from vaccine recipients

P. A. Rota, Ali S Khan, E. Durigon, T. Yuran, Y. S. Villamarzo, W. J. Bellini

Research output: Contribution to journalComment/debate

62 Citations (Scopus)

Abstract

Analysis of urine specimens by using reverse transcriptase-PCR was evaluated as a rapid assay to identify individuals infected with measles virus. For the study, daily urine samples were obtained from either 15- month-old children or young adults following measles immunization. Overall, measles virus RNA was detected in 10 of 12 children during the 2-week sampling period. In some cases, measles virus RNA was detected as early as 1 day or as late as 14 days after vaccination. Measles virus RNA was also detected in the urine samples from all four of the young adults between 1 and 13 days after vaccination. This assay will enable continued studies of the shedding and transmission of measles virus and, it is hoped, will provide a rapid means to identify measles infection, especially in mild or asymptomatic cases.

Original languageEnglish (US)
Pages (from-to)2485-2488
Number of pages4
JournalJournal of clinical microbiology
Volume33
Issue number9
StatePublished - Jan 1 1995

Fingerprint

Measles virus
Vaccines
Urine
RNA
Measles
Young Adult
Vaccination
Reverse Transcriptase Polymerase Chain Reaction
Immunization
Infection

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

Cite this

Rota, P. A., Khan, A. S., Durigon, E., Yuran, T., Villamarzo, Y. S., & Bellini, W. J. (1995). Detection of measles virus RNA in urine specimens from vaccine recipients. Journal of clinical microbiology, 33(9), 2485-2488.

Detection of measles virus RNA in urine specimens from vaccine recipients. / Rota, P. A.; Khan, Ali S; Durigon, E.; Yuran, T.; Villamarzo, Y. S.; Bellini, W. J.

In: Journal of clinical microbiology, Vol. 33, No. 9, 01.01.1995, p. 2485-2488.

Research output: Contribution to journalComment/debate

Rota, PA, Khan, AS, Durigon, E, Yuran, T, Villamarzo, YS & Bellini, WJ 1995, 'Detection of measles virus RNA in urine specimens from vaccine recipients', Journal of clinical microbiology, vol. 33, no. 9, pp. 2485-2488.
Rota PA, Khan AS, Durigon E, Yuran T, Villamarzo YS, Bellini WJ. Detection of measles virus RNA in urine specimens from vaccine recipients. Journal of clinical microbiology. 1995 Jan 1;33(9):2485-2488.
Rota, P. A. ; Khan, Ali S ; Durigon, E. ; Yuran, T. ; Villamarzo, Y. S. ; Bellini, W. J. / Detection of measles virus RNA in urine specimens from vaccine recipients. In: Journal of clinical microbiology. 1995 ; Vol. 33, No. 9. pp. 2485-2488.
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