Depression in Parkinson’s disease

Steven Phillip Wengel, Dennis P McNeilly, William J. Burke

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

Depression is the most common psychiatric complication affecting persons with Parkinson’s disease (PD). Depressive symptoms may affect as many as half of all PD patients at some point in their illness, and in many cases, depressive symptoms actually predate motor signs and symptoms. Aggressive surveillance for and treatment of depression is critical since untreated depression produces a great deal of human suffering both in patients themselves and in those who care for them, and depression is usually treatable. In PD patients, depression may have even more impact on functional status than in other patients with depression. However, there is still uncertainty about many aspects of depression in PD despite an increasing amount of research devoted to this topic. In particular, issues revolving around differentiating depression from PD symptoms, the role of cognitive impairment from PD on mood symptoms, and unique treatment concerns in this population can be challenging for the clinician. This chapter will provide an update on what is known about depression in PD, including its epidemiology, neurobiological factors, clinical features, neuropsychological features, and treatment.

Original languageEnglish (US)
Title of host publicationParkinson's Disease, Second Edition
PublisherCRC Press
Pages385-395
Number of pages11
ISBN (Electronic)9781439807156
ISBN (Print)9781439807149
DOIs
StatePublished - Jan 1 2012

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Parkinson Disease
Depression
Prednisolone
Psychological Stress
Signs and Symptoms
Uncertainty
Psychiatry
Epidemiology
Therapeutics
Research

ASJC Scopus subject areas

  • Neuroscience(all)
  • Medicine(all)

Cite this

Wengel, S. P., McNeilly, D. P., & Burke, W. J. (2012). Depression in Parkinson’s disease. In Parkinson's Disease, Second Edition (pp. 385-395). CRC Press. https://doi.org/10.1201/b12948

Depression in Parkinson’s disease. / Wengel, Steven Phillip; McNeilly, Dennis P; Burke, William J.

Parkinson's Disease, Second Edition. CRC Press, 2012. p. 385-395.

Research output: Chapter in Book/Report/Conference proceedingChapter

Wengel, SP, McNeilly, DP & Burke, WJ 2012, Depression in Parkinson’s disease. in Parkinson's Disease, Second Edition. CRC Press, pp. 385-395. https://doi.org/10.1201/b12948
Wengel SP, McNeilly DP, Burke WJ. Depression in Parkinson’s disease. In Parkinson's Disease, Second Edition. CRC Press. 2012. p. 385-395 https://doi.org/10.1201/b12948
Wengel, Steven Phillip ; McNeilly, Dennis P ; Burke, William J. / Depression in Parkinson’s disease. Parkinson's Disease, Second Edition. CRC Press, 2012. pp. 385-395
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