Abstract

Objective Though depression often afflicts head and neck cancer (HNC) patients, few studies have examined the association between depression and survival in this particular cancer population. The objective of this study is to investigate the five-year survival of HNC patients by depression status. Materials and methods This study used SEER-Medicare data from 2002–2010 and identified depression diagnosis two years before and one year after cancer diagnosis. HNC patients were identified using ICD-O3 codes and depression was identified using ICD-9-CM codes from Medicare claims. Results Of the 3466 patients included in the study, 642 (18.5%) were diagnosed with depression during the study period. Compared to those who received no depression diagnosis, those diagnosed with depression prior to cancer or after cancer diagnosis were more likely to die of cancer (HR = 1.49; 95% CI = 1.27, 1.76 and HR = 1.38; 95% CI = 1.16, 1.65, respectively). Similarly, when looking at death from any cause, those diagnosed with depression prior to cancer diagnosis and those who received a diagnosis of depression after cancer were more likely to die from any death compared to those without depression (HR = 1.55; 95% CI = 1.36, 1.76 and HR = 1.40; 95% CI = 1.21, 1.62, respectively). Conclusions The results emphasize the need for early identification and treatment of depression in HNC patients, as well as the establishment of policies to routinely screen these patients throughout the cancer treatment process.

Original languageEnglish (US)
Pages (from-to)76-82
Number of pages7
JournalOral Oncology
Volume65
DOIs
StatePublished - Feb 1 2017

Fingerprint

Head and Neck Neoplasms
Survival
Neoplasms
International Classification of Diseases
Medicare
Cause of Death
Therapeutics
Population

Keywords

  • Cancer
  • Depression
  • Epidemiology
  • Head and neck cancer
  • Oncology
  • SEER-Medicare
  • Survival

ASJC Scopus subject areas

  • Oral Surgery
  • Oncology
  • Cancer Research

Cite this

Depression and survival in head and neck cancer patients. / Rieke, Katherine; Schmid, Kendra K; Lydiatt, William; Houfek, Julia; Boilesen, Eugene; Watanabe-Galloway, Shinobu.

In: Oral Oncology, Vol. 65, 01.02.2017, p. 76-82.

Research output: Contribution to journalArticle

Rieke, Katherine ; Schmid, Kendra K ; Lydiatt, William ; Houfek, Julia ; Boilesen, Eugene ; Watanabe-Galloway, Shinobu. / Depression and survival in head and neck cancer patients. In: Oral Oncology. 2017 ; Vol. 65. pp. 76-82.
@article{4943a291bcbb4c0e9a462bea45b99366,
title = "Depression and survival in head and neck cancer patients",
abstract = "Objective Though depression often afflicts head and neck cancer (HNC) patients, few studies have examined the association between depression and survival in this particular cancer population. The objective of this study is to investigate the five-year survival of HNC patients by depression status. Materials and methods This study used SEER-Medicare data from 2002–2010 and identified depression diagnosis two years before and one year after cancer diagnosis. HNC patients were identified using ICD-O3 codes and depression was identified using ICD-9-CM codes from Medicare claims. Results Of the 3466 patients included in the study, 642 (18.5{\%}) were diagnosed with depression during the study period. Compared to those who received no depression diagnosis, those diagnosed with depression prior to cancer or after cancer diagnosis were more likely to die of cancer (HR = 1.49; 95{\%} CI = 1.27, 1.76 and HR = 1.38; 95{\%} CI = 1.16, 1.65, respectively). Similarly, when looking at death from any cause, those diagnosed with depression prior to cancer diagnosis and those who received a diagnosis of depression after cancer were more likely to die from any death compared to those without depression (HR = 1.55; 95{\%} CI = 1.36, 1.76 and HR = 1.40; 95{\%} CI = 1.21, 1.62, respectively). Conclusions The results emphasize the need for early identification and treatment of depression in HNC patients, as well as the establishment of policies to routinely screen these patients throughout the cancer treatment process.",
keywords = "Cancer, Depression, Epidemiology, Head and neck cancer, Oncology, SEER-Medicare, Survival",
author = "Katherine Rieke and Schmid, {Kendra K} and William Lydiatt and Julia Houfek and Eugene Boilesen and Shinobu Watanabe-Galloway",
year = "2017",
month = "2",
day = "1",
doi = "10.1016/j.oraloncology.2016.12.014",
language = "English (US)",
volume = "65",
pages = "76--82",
journal = "Oral Oncology",
issn = "1368-8375",
publisher = "Elsevier Limited",

}

TY - JOUR

T1 - Depression and survival in head and neck cancer patients

AU - Rieke, Katherine

AU - Schmid, Kendra K

AU - Lydiatt, William

AU - Houfek, Julia

AU - Boilesen, Eugene

AU - Watanabe-Galloway, Shinobu

PY - 2017/2/1

Y1 - 2017/2/1

N2 - Objective Though depression often afflicts head and neck cancer (HNC) patients, few studies have examined the association between depression and survival in this particular cancer population. The objective of this study is to investigate the five-year survival of HNC patients by depression status. Materials and methods This study used SEER-Medicare data from 2002–2010 and identified depression diagnosis two years before and one year after cancer diagnosis. HNC patients were identified using ICD-O3 codes and depression was identified using ICD-9-CM codes from Medicare claims. Results Of the 3466 patients included in the study, 642 (18.5%) were diagnosed with depression during the study period. Compared to those who received no depression diagnosis, those diagnosed with depression prior to cancer or after cancer diagnosis were more likely to die of cancer (HR = 1.49; 95% CI = 1.27, 1.76 and HR = 1.38; 95% CI = 1.16, 1.65, respectively). Similarly, when looking at death from any cause, those diagnosed with depression prior to cancer diagnosis and those who received a diagnosis of depression after cancer were more likely to die from any death compared to those without depression (HR = 1.55; 95% CI = 1.36, 1.76 and HR = 1.40; 95% CI = 1.21, 1.62, respectively). Conclusions The results emphasize the need for early identification and treatment of depression in HNC patients, as well as the establishment of policies to routinely screen these patients throughout the cancer treatment process.

AB - Objective Though depression often afflicts head and neck cancer (HNC) patients, few studies have examined the association between depression and survival in this particular cancer population. The objective of this study is to investigate the five-year survival of HNC patients by depression status. Materials and methods This study used SEER-Medicare data from 2002–2010 and identified depression diagnosis two years before and one year after cancer diagnosis. HNC patients were identified using ICD-O3 codes and depression was identified using ICD-9-CM codes from Medicare claims. Results Of the 3466 patients included in the study, 642 (18.5%) were diagnosed with depression during the study period. Compared to those who received no depression diagnosis, those diagnosed with depression prior to cancer or after cancer diagnosis were more likely to die of cancer (HR = 1.49; 95% CI = 1.27, 1.76 and HR = 1.38; 95% CI = 1.16, 1.65, respectively). Similarly, when looking at death from any cause, those diagnosed with depression prior to cancer diagnosis and those who received a diagnosis of depression after cancer were more likely to die from any death compared to those without depression (HR = 1.55; 95% CI = 1.36, 1.76 and HR = 1.40; 95% CI = 1.21, 1.62, respectively). Conclusions The results emphasize the need for early identification and treatment of depression in HNC patients, as well as the establishment of policies to routinely screen these patients throughout the cancer treatment process.

KW - Cancer

KW - Depression

KW - Epidemiology

KW - Head and neck cancer

KW - Oncology

KW - SEER-Medicare

KW - Survival

UR - http://www.scopus.com/inward/record.url?scp=85007495106&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85007495106&partnerID=8YFLogxK

U2 - 10.1016/j.oraloncology.2016.12.014

DO - 10.1016/j.oraloncology.2016.12.014

M3 - Article

VL - 65

SP - 76

EP - 82

JO - Oral Oncology

JF - Oral Oncology

SN - 1368-8375

ER -