Dataset on the chemokine and cytokine responses of multi-cell cultures treated with Porphyromonas gingivalis hemagglutinin B

Vrushali P. Abhyankar, Amber M. Bates, Carol L. Fischer, Georgia K. Johnson, Janet M. Guthmiller, Ann Progulske-Fox, Kim A. Brogden

Research output: Contribution to journalArticle

Abstract

Chemokines and cytokines produced in gingival tissues exposed to microorganisms and microbial products in dental plaque lead to local inflammation and tissue damage seen in periodontal disease. Bates et al. 2018 [1] reported that Porphyromonas gingivalis hemagglutinin B (HagB)-induced matrix metalloproteinase (MMP) responses of single cell cultures containing dendritic cells, gingival epithelial (GE) keratinocytes, or T cells were significantly different from the MMP responses of these same cells grown in multi-cell cultures. Here we report the concentrations (pg/ml) of HagB-induced IL1α IL6, IL8, IL12(p40), GM-CSF, MIP1α MIP1β RANTES, TNFα and VEGF produced by dendritic cells, GE keratinocytes, or T cells in single cell cultures, two-cell cultures, or three-cell cultures.

Original languageEnglish (US)
Pages (from-to)964-970
Number of pages7
JournalData in Brief
Volume22
DOIs
StatePublished - Feb 2019

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Chemokines
Cell Culture Techniques
Cytokines
Matrix Metalloproteinases
Keratinocytes
Dendritic Cells
Epithelial Cells
T-Lymphocytes
Chemokine CCL5
Dental Plaque
Hemagglutinins
Periodontal Diseases
Interleukin-12
Granulocyte-Macrophage Colony-Stimulating Factor
Interleukin-8
Vascular Endothelial Growth Factor A
Interleukin-6
Datasets
Porphyromonas gingivalis HagB protein
Inflammation

Keywords

  • Cytokines
  • Dendritic cells
  • Hemagglutinin B
  • Keratinocytes
  • Periodontal disease
  • Porphyromonas gingivalis
  • T cells

ASJC Scopus subject areas

  • General

Cite this

Dataset on the chemokine and cytokine responses of multi-cell cultures treated with Porphyromonas gingivalis hemagglutinin B. / Abhyankar, Vrushali P.; Bates, Amber M.; Fischer, Carol L.; Johnson, Georgia K.; Guthmiller, Janet M.; Progulske-Fox, Ann; Brogden, Kim A.

In: Data in Brief, Vol. 22, 02.2019, p. 964-970.

Research output: Contribution to journalArticle

Abhyankar, Vrushali P. ; Bates, Amber M. ; Fischer, Carol L. ; Johnson, Georgia K. ; Guthmiller, Janet M. ; Progulske-Fox, Ann ; Brogden, Kim A. / Dataset on the chemokine and cytokine responses of multi-cell cultures treated with Porphyromonas gingivalis hemagglutinin B. In: Data in Brief. 2019 ; Vol. 22. pp. 964-970.
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AU - Abhyankar, Vrushali P.

AU - Bates, Amber M.

AU - Fischer, Carol L.

AU - Johnson, Georgia K.

AU - Guthmiller, Janet M.

AU - Progulske-Fox, Ann

AU - Brogden, Kim A.

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KW - Dendritic cells

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KW - Keratinocytes

KW - Periodontal disease

KW - Porphyromonas gingivalis

KW - T cells

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