Cytomegalovirus cecal erosion causing massive hemorrhage in a bone marrow transplant recipient

John C. West, James O. Armitage, Frank A. Mitros, Lynell W. Klassen, Robert J. Corry, Thomas Ray

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

A 24-year-old male underwent bone marrow transplantation for severe aplastic anemia. Posttransplantation complications included severe graft-versus-host disease and cytomegalovirus (CMV) infection manifested by gastrointestinal bleeding and apparent pneumonitis. Massive rectal bleeding necessitated exploratory laparotomy at which time a right colon resection was performed. Fifteen cecal ulcers were present which on histologixc examination revealed numerous cells containing characteristic intranuclear inclusions. Life-threatening gastrointestinal lesions associated with CMV infection will be seen with increasing frequency as more patients undergo the severe immunosuppression associated with bone marrow and organ transplantation. Prompt recognition and expeditious surgical management will result in improved survival in this high-risk population.

Original languageEnglish (US)
Pages (from-to)251-254
Number of pages4
JournalWorld Journal of Surgery
Volume6
Issue number2
DOIs
StatePublished - Mar 1 1982

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Cytomegalovirus Infections
Cytomegalovirus
Bone Marrow Transplantation
Bone Marrow
Hemorrhage
Intranuclear Inclusion Bodies
Aplastic Anemia
Organ Transplantation
Graft vs Host Disease
Laparotomy
Immunosuppression
Ulcer
Pneumonia
Colon
Survival
Population
Transplant Recipients

ASJC Scopus subject areas

  • Surgery

Cite this

Cytomegalovirus cecal erosion causing massive hemorrhage in a bone marrow transplant recipient. / West, John C.; Armitage, James O.; Mitros, Frank A.; Klassen, Lynell W.; Corry, Robert J.; Ray, Thomas.

In: World Journal of Surgery, Vol. 6, No. 2, 01.03.1982, p. 251-254.

Research output: Contribution to journalArticle

West, John C. ; Armitage, James O. ; Mitros, Frank A. ; Klassen, Lynell W. ; Corry, Robert J. ; Ray, Thomas. / Cytomegalovirus cecal erosion causing massive hemorrhage in a bone marrow transplant recipient. In: World Journal of Surgery. 1982 ; Vol. 6, No. 2. pp. 251-254.
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