Cytogenetic abnormalities in b-immunoblastic lymphoma

Marcus B. Nashelsky, Michelle M. Hess, Dennis D. Weisenburger, Jene L. Pierson, Martin A. Bast, James O. Armitage, Warren G. Sanger

Research output: Contribution to journalArticle

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Abstract

We have considered the cytogenetic abnormalities present in 27 unpublished cases of B-immunoblastic lymphoma. Among these 27 patients, the chromosome changes were heterogeneous and complex. The chromosomes most commonly gained were 3 (44% of cases), 18 (44% 6 (30% and 11 (30% The most common structural abnormalities involved band 14q32 (26% band 18q21 (15% and bands 6q 16-21 (19% Study of these 27 immunoblastic lymphomas did not allow us to tentatively identify a common primary cytogenetic abnormality unique to B-immunoblastic lymphoma, however, a translocation at 14q32 may be the primary cytogenetic lesion in some of the cases. Rather, we have added to the number of abnormalities reported in immunoblastic lymphoma and in non-Hodgkin's lymphoma in general.

Original languageEnglish (US)
Pages (from-to)415-420
Number of pages6
JournalLeukemia and Lymphoma
Volume14
Issue number5-6
DOIs
StatePublished - Jan 1 1994

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Chromosome Aberrations
Lymphoma
Chromosomes
Cytogenetics
Non-Hodgkin's Lymphoma

Keywords

  • B-immunoblastic lymphoma
  • Chromosomes
  • Lymphoma
  • Non-Hodgkin's lymphoma

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

Cite this

Nashelsky, M. B., Hess, M. M., Weisenburger, D. D., Pierson, J. L., Bast, M. A., Armitage, J. O., & Sanger, W. G. (1994). Cytogenetic abnormalities in b-immunoblastic lymphoma. Leukemia and Lymphoma, 14(5-6), 415-420. https://doi.org/10.3109/10428199409049698

Cytogenetic abnormalities in b-immunoblastic lymphoma. / Nashelsky, Marcus B.; Hess, Michelle M.; Weisenburger, Dennis D.; Pierson, Jene L.; Bast, Martin A.; Armitage, James O.; Sanger, Warren G.

In: Leukemia and Lymphoma, Vol. 14, No. 5-6, 01.01.1994, p. 415-420.

Research output: Contribution to journalArticle

Nashelsky, MB, Hess, MM, Weisenburger, DD, Pierson, JL, Bast, MA, Armitage, JO & Sanger, WG 1994, 'Cytogenetic abnormalities in b-immunoblastic lymphoma', Leukemia and Lymphoma, vol. 14, no. 5-6, pp. 415-420. https://doi.org/10.3109/10428199409049698
Nashelsky MB, Hess MM, Weisenburger DD, Pierson JL, Bast MA, Armitage JO et al. Cytogenetic abnormalities in b-immunoblastic lymphoma. Leukemia and Lymphoma. 1994 Jan 1;14(5-6):415-420. https://doi.org/10.3109/10428199409049698
Nashelsky, Marcus B. ; Hess, Michelle M. ; Weisenburger, Dennis D. ; Pierson, Jene L. ; Bast, Martin A. ; Armitage, James O. ; Sanger, Warren G. / Cytogenetic abnormalities in b-immunoblastic lymphoma. In: Leukemia and Lymphoma. 1994 ; Vol. 14, No. 5-6. pp. 415-420.
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