9 Citations (Scopus)

Abstract

Despite a decreasing incidence in the United States, small-cell lung cancer (SCLC) remains a major clinical problem, with approximately 30,000 new cases each year. The diagnosis of SCLC is usually not difficult. The Veterans Administration Lung Study Group (VALSG) staging system is less accurate than the American Joint Committee of Cancer tumor-node-metastasis (TNM) system (7th edition) at predicting survival in SCLC, especially in lower stage disease. Surgery has not played a major part in the management of SCLC, but emerging data suggest that resection may have a role in earlier stage disease. While the frontline treatment of SCLC has not changed significantly in the past decade, newer agents that are currently being investigated provide hope for better treatment of relapsed/refractory disease for the future.

Original languageEnglish (US)
JournalONCOLOGY
Volume24
Issue number11
StatePublished - Oct 2010

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Small Cell Lung Carcinoma
United States Department of Veterans Affairs
Neoplasms
Neoplasm Metastasis
Lung
Incidence

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Current concepts in the diagnosis and management of small-cell lung cancer. / Ganti, Apar Kishor P; West, William W.; Lackner, Rudy P; Kessinger, Anne.

In: ONCOLOGY, Vol. 24, No. 11, 10.2010.

Research output: Contribution to journalArticle

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AB - Despite a decreasing incidence in the United States, small-cell lung cancer (SCLC) remains a major clinical problem, with approximately 30,000 new cases each year. The diagnosis of SCLC is usually not difficult. The Veterans Administration Lung Study Group (VALSG) staging system is less accurate than the American Joint Committee of Cancer tumor-node-metastasis (TNM) system (7th edition) at predicting survival in SCLC, especially in lower stage disease. Surgery has not played a major part in the management of SCLC, but emerging data suggest that resection may have a role in earlier stage disease. While the frontline treatment of SCLC has not changed significantly in the past decade, newer agents that are currently being investigated provide hope for better treatment of relapsed/refractory disease for the future.

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