Cost of deep brain stimulation for the treatment of Parkinson's disease by surgical stimulation sites

Kevin T. Stroupe, Frances M. Weaver, Lishan Cao, Dolores Ippolito, Brandon R. Barton, Inger E. Burnett-Zeigler, Robert G. Holloway, Barbara G. Vickrey, Tanya Simuni, Kenneth A Follett

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Objective: To assess costs and effectiveness of deep brain stimulation (DBS) of the internal globus pallidum (GPi) versus subthalamic nucleus (STN) from the provider and societal perspectives for Parkinson's disease (PD) patients in a multicenter randomized trial. Methods: All costs from randomization to 36 months were included. Costs were from Department of Veterans Affairs (VA) and Medicare databases and clinical trial data. Quality adjusted life years (QALYs) were from Quality of Well Being questionnaires. Results: Provider costs were similar for the 144 GPi and 130 STN patients (GPi: $138,044 vs. STN: $131,822; difference = $6,222, 95% confidence interval [CI]: -$42,125 to $45,343). Societal costs were also similar (GPi: $171,061 vs. STN: $167,706; difference = $3,356, 95% CI: -$57,371 to $60,294). The GPi patients had nonsignificantly more QALYs. Conclusions: The QALYs and costs were similar; the level of uncertainty given the sample size suggests that these factors should not direct treatment or resource allocation decisions in selecting or making available either procedure for eligible PD patients.

Original languageEnglish (US)
Pages (from-to)1666-1674
Number of pages9
JournalMovement Disorders
Volume29
Issue number13
DOIs
StatePublished - Nov 1 2014

Fingerprint

Globus Pallidus
Deep Brain Stimulation
Subthalamic Nucleus
Parkinson Disease
Quality-Adjusted Life Years
Costs and Cost Analysis
Confidence Intervals
Therapeutics
Resource Allocation
Veterans
Random Allocation
Medicare
Sample Size
Multicenter Studies
Uncertainty
Cost-Benefit Analysis
Clinical Trials
Databases

Keywords

  • Cost
  • Deep brain stimulation
  • Parkinson's disease

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

Stroupe, K. T., Weaver, F. M., Cao, L., Ippolito, D., Barton, B. R., Burnett-Zeigler, I. E., ... Follett, K. A. (2014). Cost of deep brain stimulation for the treatment of Parkinson's disease by surgical stimulation sites. Movement Disorders, 29(13), 1666-1674. https://doi.org/10.1002/mds.26029

Cost of deep brain stimulation for the treatment of Parkinson's disease by surgical stimulation sites. / Stroupe, Kevin T.; Weaver, Frances M.; Cao, Lishan; Ippolito, Dolores; Barton, Brandon R.; Burnett-Zeigler, Inger E.; Holloway, Robert G.; Vickrey, Barbara G.; Simuni, Tanya; Follett, Kenneth A.

In: Movement Disorders, Vol. 29, No. 13, 01.11.2014, p. 1666-1674.

Research output: Contribution to journalArticle

Stroupe, KT, Weaver, FM, Cao, L, Ippolito, D, Barton, BR, Burnett-Zeigler, IE, Holloway, RG, Vickrey, BG, Simuni, T & Follett, KA 2014, 'Cost of deep brain stimulation for the treatment of Parkinson's disease by surgical stimulation sites', Movement Disorders, vol. 29, no. 13, pp. 1666-1674. https://doi.org/10.1002/mds.26029
Stroupe KT, Weaver FM, Cao L, Ippolito D, Barton BR, Burnett-Zeigler IE et al. Cost of deep brain stimulation for the treatment of Parkinson's disease by surgical stimulation sites. Movement Disorders. 2014 Nov 1;29(13):1666-1674. https://doi.org/10.1002/mds.26029
Stroupe, Kevin T. ; Weaver, Frances M. ; Cao, Lishan ; Ippolito, Dolores ; Barton, Brandon R. ; Burnett-Zeigler, Inger E. ; Holloway, Robert G. ; Vickrey, Barbara G. ; Simuni, Tanya ; Follett, Kenneth A. / Cost of deep brain stimulation for the treatment of Parkinson's disease by surgical stimulation sites. In: Movement Disorders. 2014 ; Vol. 29, No. 13. pp. 1666-1674.
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