COPD heterogeneity: What this will mean in practice

Stephen I. Rennard

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

COPD is a complex collection of conditions. All share the feature of limited expiratory air flow. It is a "disease" in the same sense as is "chronic renal failure." Like most other chronic organ failure "diseases," COPD has disparate causes, and patients are heterogeneous in their prognosis and response to treatment. Unlike many other diseases, the heterogeneity of COPD is just beginning to be described. A number of large trials funded by the National Institutes of Health and industry promise to refine the classification of COPD. Based on accurate diagnosis of COPD subtypes, novel treatments can be more effectively developed and implemented. The clinical implications of improved understanding of COPD heterogeneity will be better care and outcomes for COPD patients, which will depend on increased diagnostic accuracy and selective administration of treatments.

Original languageEnglish (US)
Pages (from-to)1181-1187
Number of pages7
JournalRespiratory Care
Volume56
Issue number8
DOIs
StatePublished - Aug 1 2011

Fingerprint

Chronic Obstructive Pulmonary Disease
National Institutes of Health (U.S.)
Chronic Kidney Failure
Industry
Therapeutics
Air

Keywords

  • COPD
  • Chronic obstructive pulmonary disease

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine

Cite this

COPD heterogeneity : What this will mean in practice. / Rennard, Stephen I.

In: Respiratory Care, Vol. 56, No. 8, 01.08.2011, p. 1181-1187.

Research output: Contribution to journalArticle

Rennard, Stephen I. / COPD heterogeneity : What this will mean in practice. In: Respiratory Care. 2011 ; Vol. 56, No. 8. pp. 1181-1187.
@article{b7bcb3a056964a6da1f72b06e1dfedb2,
title = "COPD heterogeneity: What this will mean in practice",
abstract = "COPD is a complex collection of conditions. All share the feature of limited expiratory air flow. It is a {"}disease{"} in the same sense as is {"}chronic renal failure.{"} Like most other chronic organ failure {"}diseases,{"} COPD has disparate causes, and patients are heterogeneous in their prognosis and response to treatment. Unlike many other diseases, the heterogeneity of COPD is just beginning to be described. A number of large trials funded by the National Institutes of Health and industry promise to refine the classification of COPD. Based on accurate diagnosis of COPD subtypes, novel treatments can be more effectively developed and implemented. The clinical implications of improved understanding of COPD heterogeneity will be better care and outcomes for COPD patients, which will depend on increased diagnostic accuracy and selective administration of treatments.",
keywords = "COPD, Chronic obstructive pulmonary disease",
author = "Rennard, {Stephen I.}",
year = "2011",
month = "8",
day = "1",
doi = "10.4187/respcare.01419",
language = "English (US)",
volume = "56",
pages = "1181--1187",
journal = "Respiratory Care",
issn = "0098-9142",
publisher = "Daedalus Enterprises Inc.",
number = "8",

}

TY - JOUR

T1 - COPD heterogeneity

T2 - What this will mean in practice

AU - Rennard, Stephen I.

PY - 2011/8/1

Y1 - 2011/8/1

N2 - COPD is a complex collection of conditions. All share the feature of limited expiratory air flow. It is a "disease" in the same sense as is "chronic renal failure." Like most other chronic organ failure "diseases," COPD has disparate causes, and patients are heterogeneous in their prognosis and response to treatment. Unlike many other diseases, the heterogeneity of COPD is just beginning to be described. A number of large trials funded by the National Institutes of Health and industry promise to refine the classification of COPD. Based on accurate diagnosis of COPD subtypes, novel treatments can be more effectively developed and implemented. The clinical implications of improved understanding of COPD heterogeneity will be better care and outcomes for COPD patients, which will depend on increased diagnostic accuracy and selective administration of treatments.

AB - COPD is a complex collection of conditions. All share the feature of limited expiratory air flow. It is a "disease" in the same sense as is "chronic renal failure." Like most other chronic organ failure "diseases," COPD has disparate causes, and patients are heterogeneous in their prognosis and response to treatment. Unlike many other diseases, the heterogeneity of COPD is just beginning to be described. A number of large trials funded by the National Institutes of Health and industry promise to refine the classification of COPD. Based on accurate diagnosis of COPD subtypes, novel treatments can be more effectively developed and implemented. The clinical implications of improved understanding of COPD heterogeneity will be better care and outcomes for COPD patients, which will depend on increased diagnostic accuracy and selective administration of treatments.

KW - COPD

KW - Chronic obstructive pulmonary disease

UR - http://www.scopus.com/inward/record.url?scp=80051478532&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80051478532&partnerID=8YFLogxK

U2 - 10.4187/respcare.01419

DO - 10.4187/respcare.01419

M3 - Article

C2 - 21801580

AN - SCOPUS:80051478532

VL - 56

SP - 1181

EP - 1187

JO - Respiratory Care

JF - Respiratory Care

SN - 0098-9142

IS - 8

ER -