Controlling mode selectivity in palladium-catalyzed bisdiene carbocyclizations: Optimizing for cyclization-trapping over cycloisomerization

James M. Takacs, Scott D. Schroeder, Jianxin Han, Meg Gifford, Xun Tian Jiang, Twana Saleh, Suresh Vayalakkada, Amy H. Yap

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

[Equation presented] Screening combinations of five catalyst precursors with 13 phosphorus ligands identified cyclization catalysts that favor carbocyclization-trapping with N-hydroxyphthalimide over a competing cycloisomerization mode.

Original languageEnglish (US)
Pages (from-to)3595-3598
Number of pages4
JournalOrganic Letters
Volume5
Issue number20
DOIs
StatePublished - Oct 2 2003

Fingerprint

Cyclization
Palladium
Phosphorus
palladium
selectivity
trapping
Ligands
catalysts
Catalysts
phosphorus
Screening
screening
ligands
N-hydroxyphthalimide

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

Controlling mode selectivity in palladium-catalyzed bisdiene carbocyclizations : Optimizing for cyclization-trapping over cycloisomerization. / Takacs, James M.; Schroeder, Scott D.; Han, Jianxin; Gifford, Meg; Jiang, Xun Tian; Saleh, Twana; Vayalakkada, Suresh; Yap, Amy H.

In: Organic Letters, Vol. 5, No. 20, 02.10.2003, p. 3595-3598.

Research output: Contribution to journalArticle

Takacs, James M. ; Schroeder, Scott D. ; Han, Jianxin ; Gifford, Meg ; Jiang, Xun Tian ; Saleh, Twana ; Vayalakkada, Suresh ; Yap, Amy H. / Controlling mode selectivity in palladium-catalyzed bisdiene carbocyclizations : Optimizing for cyclization-trapping over cycloisomerization. In: Organic Letters. 2003 ; Vol. 5, No. 20. pp. 3595-3598.
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