Contributions of phenotypic plasticity to differences in thermogenic performance between highland and lowland deer mice

Zachary A. Cheviron, Gwendolyn C. Bachman, Jay F. Storz

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Small mammals face especially severe thermoregulatory challenges at high altitude because the reduced O2 availability constrains the capacity for aerobic thermogenesis. Adaptive enhancement of thermogenic performance under hypoxic conditions may be achieved via physiological adjustments that occur within the lifetime of individuals (phenotypic plasticity) and/or genetically based changes that occur across generations, but their relative contributions to performance differences between highland and lowland natives are unclear. Here, we examined potentially evolved differences in thermogenic performance between populations of deer mice (Peromyscus maniculatus) that are native to different altitudes. The purpose of the study was to assess the contribution of phenotypic plasticity to population differences in thermogenic performance under hypoxia. We used a common-garden deacclimation experiment to demonstrate that highland deer mice have enhanced thermogenic capacities under hypoxia, and that performance differences between highland and lowland mice persist when individuals are born and reared under common-garden conditions, suggesting that differences in thermogenic capacity have a genetic basis. Conversely, population differences in thermogenic endurance appear to be entirely attributable to physiological plasticity during adulthood. These combined results reveal distinct sources of phenotypic plasticity for different aspects of thermogenic performance, and suggest that thermogenic capacity and endurance may have different mechanistic underpinnings.

Original languageEnglish (US)
Pages (from-to)1160-1166
Number of pages7
JournalJournal of Experimental Biology
Volume216
Issue number7
DOIs
StatePublished - Apr 1 2013

Fingerprint

Peromyscus
phenotypic plasticity
deer
lowlands
highlands
hypoxia
gardens
garden
Population
Peromyscus maniculatus
Thermogenesis
small mammal
heat production
adulthood
small mammals
Population Groups
anaerobic conditions
plasticity
Mammals
mice

Keywords

  • Developmental plasticity
  • High-altitude adaptation
  • Hypoxia
  • Peromyscus
  • Thermoregulation

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Physiology
  • Aquatic Science
  • Animal Science and Zoology
  • Molecular Biology
  • Insect Science

Cite this

Contributions of phenotypic plasticity to differences in thermogenic performance between highland and lowland deer mice. / Cheviron, Zachary A.; Bachman, Gwendolyn C.; Storz, Jay F.

In: Journal of Experimental Biology, Vol. 216, No. 7, 01.04.2013, p. 1160-1166.

Research output: Contribution to journalArticle

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