Conscious recollection and the human hippocampal formation: Evidence from positron emission tomography

Daniel L. Schacter, Nathaniel M. Alpert, Cary R. Savage, Scott L. Rauch, Marilyn S. Albert

Research output: Contribution to journalArticle

504 Citations (Scopus)

Abstract

We used positron emission tomography (PET) to examine the role of the hippocampal formation in implicit and explicit memory. Human volunteers studied a list of familiar words, and then they either provided the first word that came to mind in response to three-letter cues (implicit memory) or tried to recall studied words in response to the same cues (explicit memory). There was no evidence of hippocampal activation in association with implicit memory. However, priming effects on the implicit memory test were associated with decreased activity in extrastriate visual cortex. On the explicit memory test, subjects recalled many target words in one condition and recalled few words in a second condition, despite trying to remember them. Comparisons between the two conditions showed that blood-flow increases in the hippocampal formation are specifically associated with the conscious recollection of studied words, whereas blood-flow increases in frontal regions are associated with efforts to retrieve target words. Our results help to clarify some puzzles concerning the rule of the hippocampal formation in human memory.

Original languageEnglish (US)
Pages (from-to)321-325
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Volume93
Issue number1
DOIs
StatePublished - Jan 9 1996

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Positron-Emission Tomography
Hippocampus
Visual Cortex
Cues
Volunteers

Keywords

  • frontal lobes
  • hippocampus
  • memory
  • visual cortex

ASJC Scopus subject areas

  • General

Cite this

Conscious recollection and the human hippocampal formation : Evidence from positron emission tomography. / Schacter, Daniel L.; Alpert, Nathaniel M.; Savage, Cary R.; Rauch, Scott L.; Albert, Marilyn S.

In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, No. 1, 09.01.1996, p. 321-325.

Research output: Contribution to journalArticle

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