Conjunctival Lesions Caused by Moraxella bovis in Gnotobiotic Calves

D. G. Rogers, N. F. Cheville, G. W. Pugh

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Hemolytic Moraxella bovis was instilled into the conjunctival sac of gnotobiotic calves, and conjunctivae were sampled serially after infection. Bilateral lesions developed in seven of eight infected calves. Histologically, M. bovis was first seen within swollen epithelial cells near the lid margins and occasionally within superficial epithelium in other areas. Conjunctival erosions and ulcers were seen in later stages. Scanning electron microscopy showed M. bovis in pits on surfaces of epithelial cells and in erosions on palpebral conjunctivae; lesions were prominent near lid margins. By transmission electron microscopy, M. bovis was seen within swollen epithelial cells near lid margins; many epithelial cells had undergone cytolysis. This study demonstrates that virulent M. bovis can invade bovine conjunctival epithelial cells and cause conjunctivitis in the absence of injurious ultraviolet irradiation or other predisposing environmental factors.

Original languageEnglish (US)
Pages (from-to)554-559
Number of pages6
JournalVeterinary pathology
Volume24
Issue number6
DOIs
StatePublished - Nov 1987

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Moraxella (Moraxella) bovis
Moraxella bovis
Germ-Free Life
lesions (animal)
epithelial cells
Epithelial Cells
lids
calves
conjunctiva
Conjunctiva
cytolysis
lacrimal apparatus
Lacrimal Apparatus
conjunctivitis
Conjunctivitis
eyelids
Transmission Electron Microscopy
Causality
Electron Scanning Microscopy
Ulcer

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Conjunctival Lesions Caused by Moraxella bovis in Gnotobiotic Calves. / Rogers, D. G.; Cheville, N. F.; Pugh, G. W.

In: Veterinary pathology, Vol. 24, No. 6, 11.1987, p. 554-559.

Research output: Contribution to journalArticle

Rogers, D. G. ; Cheville, N. F. ; Pugh, G. W. / Conjunctival Lesions Caused by Moraxella bovis in Gnotobiotic Calves. In: Veterinary pathology. 1987 ; Vol. 24, No. 6. pp. 554-559.
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