Comparison of conventional periodontal maintenance versus scaling and root planing with subgingival minocycline

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Abstract

Background: Alternative regimens using subgingival antimicrobials compared to conventional periodontal maintenance (PM) may lead to more efficient protocols. The purpose of this study was to evaluate treatment time and clinical and radiographic outcomes in 2 periodontitis cohorts, one receiving conventional PM and the other receiving scaling and root planing (SRP) and multiple doses of subgingival minocycline. Methods: Moderate to advanced chronic periodontitis patients were concurrently treated with either: 1) scaling and root planing and 4 subgingival doses of minocycline microspheres in all ≥5 mm pockets over a 6-month period (RP/M; n = 24 patients); or 2) conventional 3-month periodontal maintenance (PM; n = 24 patients). Clinical and radiographic measurements, including probing depth (PD), clinical attachment level (CAL), and interproximal bone height (BH), were analyzed in 2 premolar/molar interproximal ≥5 mm pockets at baseline and 1 year using paired t tests, analysis of variance, chi-square analysis, and correlation coefficients. Results: Baseline clinical and radiographic data were similar between RP/M and PM patients. Probing depths showed greater mean improvement in RP/M (0.9 ± 0.1 versus 0.4 ± 0.1 mm, P = 0.02), with 25% of subjects in RP/M gaining ≥2 mm compared to 4.2% in PM (differences were statistically significant). The mean loss in bone height and percent subjects losing bone height were less in RP/M (0.05 ± 0.05 mm; 12.5%) than PM (0.09 ± 0.08 mm; 16.7%), but bone height differences were not statistically significant. A subset of RP/M molar furcation sites responded with similar PD reduction and no BH loss over 1 year. While cross-sectional RP/M data between CAL and BH, or PD and CAL were highly correlated, changes over 1 year were not correlated among any of these parameters. Conclusions: Scaling and root planing and subgingival minocycline in experimental sites took little time (<5 minutes/appointment), but resulted in more probing depth reduction and less frequent bone height loss than conventional periodontal maintenance.

Original languageEnglish (US)
Pages (from-to)167-172
Number of pages6
JournalJournal of periodontology
Volume73
Issue number2
DOIs
StatePublished - Mar 21 2002

Fingerprint

Root Planing
Minocycline
Maintenance
Bone and Bones
Dental Scaling
Chronic Periodontitis
Periodontitis
Bicuspid
Microspheres
Analysis of Variance
Appointments and Schedules

Keywords

  • Bone loss/prevention and control
  • Comparison studies
  • Minocycline/therapeutic use
  • Periodontal pockets/prevention and control
  • Planing
  • Scaling
  • Tooth root

ASJC Scopus subject areas

  • Periodontics

Cite this

@article{1e7bf227cde24ee497d0f16183e9c156,
title = "Comparison of conventional periodontal maintenance versus scaling and root planing with subgingival minocycline",
abstract = "Background: Alternative regimens using subgingival antimicrobials compared to conventional periodontal maintenance (PM) may lead to more efficient protocols. The purpose of this study was to evaluate treatment time and clinical and radiographic outcomes in 2 periodontitis cohorts, one receiving conventional PM and the other receiving scaling and root planing (SRP) and multiple doses of subgingival minocycline. Methods: Moderate to advanced chronic periodontitis patients were concurrently treated with either: 1) scaling and root planing and 4 subgingival doses of minocycline microspheres in all ≥5 mm pockets over a 6-month period (RP/M; n = 24 patients); or 2) conventional 3-month periodontal maintenance (PM; n = 24 patients). Clinical and radiographic measurements, including probing depth (PD), clinical attachment level (CAL), and interproximal bone height (BH), were analyzed in 2 premolar/molar interproximal ≥5 mm pockets at baseline and 1 year using paired t tests, analysis of variance, chi-square analysis, and correlation coefficients. Results: Baseline clinical and radiographic data were similar between RP/M and PM patients. Probing depths showed greater mean improvement in RP/M (0.9 ± 0.1 versus 0.4 ± 0.1 mm, P = 0.02), with 25{\%} of subjects in RP/M gaining ≥2 mm compared to 4.2{\%} in PM (differences were statistically significant). The mean loss in bone height and percent subjects losing bone height were less in RP/M (0.05 ± 0.05 mm; 12.5{\%}) than PM (0.09 ± 0.08 mm; 16.7{\%}), but bone height differences were not statistically significant. A subset of RP/M molar furcation sites responded with similar PD reduction and no BH loss over 1 year. While cross-sectional RP/M data between CAL and BH, or PD and CAL were highly correlated, changes over 1 year were not correlated among any of these parameters. Conclusions: Scaling and root planing and subgingival minocycline in experimental sites took little time (<5 minutes/appointment), but resulted in more probing depth reduction and less frequent bone height loss than conventional periodontal maintenance.",
keywords = "Bone loss/prevention and control, Comparison studies, Minocycline/therapeutic use, Periodontal pockets/prevention and control, Planing, Scaling, Tooth root",
author = "Meinberg, {Trudy A.} and Barnes, {Caren M} and Dunning, {David G} and Reinhardt, {Richard A}",
year = "2002",
month = "3",
day = "21",
doi = "10.1902/jop.2002.73.2.167",
language = "English (US)",
volume = "73",
pages = "167--172",
journal = "Journal of Periodontology",
issn = "0022-3492",
publisher = "American Academy of Periodontology",
number = "2",

}

TY - JOUR

T1 - Comparison of conventional periodontal maintenance versus scaling and root planing with subgingival minocycline

AU - Meinberg, Trudy A.

AU - Barnes, Caren M

AU - Dunning, David G

AU - Reinhardt, Richard A

PY - 2002/3/21

Y1 - 2002/3/21

N2 - Background: Alternative regimens using subgingival antimicrobials compared to conventional periodontal maintenance (PM) may lead to more efficient protocols. The purpose of this study was to evaluate treatment time and clinical and radiographic outcomes in 2 periodontitis cohorts, one receiving conventional PM and the other receiving scaling and root planing (SRP) and multiple doses of subgingival minocycline. Methods: Moderate to advanced chronic periodontitis patients were concurrently treated with either: 1) scaling and root planing and 4 subgingival doses of minocycline microspheres in all ≥5 mm pockets over a 6-month period (RP/M; n = 24 patients); or 2) conventional 3-month periodontal maintenance (PM; n = 24 patients). Clinical and radiographic measurements, including probing depth (PD), clinical attachment level (CAL), and interproximal bone height (BH), were analyzed in 2 premolar/molar interproximal ≥5 mm pockets at baseline and 1 year using paired t tests, analysis of variance, chi-square analysis, and correlation coefficients. Results: Baseline clinical and radiographic data were similar between RP/M and PM patients. Probing depths showed greater mean improvement in RP/M (0.9 ± 0.1 versus 0.4 ± 0.1 mm, P = 0.02), with 25% of subjects in RP/M gaining ≥2 mm compared to 4.2% in PM (differences were statistically significant). The mean loss in bone height and percent subjects losing bone height were less in RP/M (0.05 ± 0.05 mm; 12.5%) than PM (0.09 ± 0.08 mm; 16.7%), but bone height differences were not statistically significant. A subset of RP/M molar furcation sites responded with similar PD reduction and no BH loss over 1 year. While cross-sectional RP/M data between CAL and BH, or PD and CAL were highly correlated, changes over 1 year were not correlated among any of these parameters. Conclusions: Scaling and root planing and subgingival minocycline in experimental sites took little time (<5 minutes/appointment), but resulted in more probing depth reduction and less frequent bone height loss than conventional periodontal maintenance.

AB - Background: Alternative regimens using subgingival antimicrobials compared to conventional periodontal maintenance (PM) may lead to more efficient protocols. The purpose of this study was to evaluate treatment time and clinical and radiographic outcomes in 2 periodontitis cohorts, one receiving conventional PM and the other receiving scaling and root planing (SRP) and multiple doses of subgingival minocycline. Methods: Moderate to advanced chronic periodontitis patients were concurrently treated with either: 1) scaling and root planing and 4 subgingival doses of minocycline microspheres in all ≥5 mm pockets over a 6-month period (RP/M; n = 24 patients); or 2) conventional 3-month periodontal maintenance (PM; n = 24 patients). Clinical and radiographic measurements, including probing depth (PD), clinical attachment level (CAL), and interproximal bone height (BH), were analyzed in 2 premolar/molar interproximal ≥5 mm pockets at baseline and 1 year using paired t tests, analysis of variance, chi-square analysis, and correlation coefficients. Results: Baseline clinical and radiographic data were similar between RP/M and PM patients. Probing depths showed greater mean improvement in RP/M (0.9 ± 0.1 versus 0.4 ± 0.1 mm, P = 0.02), with 25% of subjects in RP/M gaining ≥2 mm compared to 4.2% in PM (differences were statistically significant). The mean loss in bone height and percent subjects losing bone height were less in RP/M (0.05 ± 0.05 mm; 12.5%) than PM (0.09 ± 0.08 mm; 16.7%), but bone height differences were not statistically significant. A subset of RP/M molar furcation sites responded with similar PD reduction and no BH loss over 1 year. While cross-sectional RP/M data between CAL and BH, or PD and CAL were highly correlated, changes over 1 year were not correlated among any of these parameters. Conclusions: Scaling and root planing and subgingival minocycline in experimental sites took little time (<5 minutes/appointment), but resulted in more probing depth reduction and less frequent bone height loss than conventional periodontal maintenance.

KW - Bone loss/prevention and control

KW - Comparison studies

KW - Minocycline/therapeutic use

KW - Periodontal pockets/prevention and control

KW - Planing

KW - Scaling

KW - Tooth root

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DO - 10.1902/jop.2002.73.2.167

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AN - SCOPUS:0036198794

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JF - Journal of Periodontology

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