Comparing the effects of atrazine and an environmentally relevant mixture on estrogen-responsive gene expression in the northern leopard frog and the fathead minnow

Jonathan M. Ali, Lindsey A. Knight, Del L. D'Souza, Alan S. Kolok

Research output: Contribution to journalArticle

4 Scopus citations


In Nebraska, fish are exposed to herbicides in agricultural runoff. The study objectives were to determine 1) if fathead minnows and northern leopard frogs exposed to atrazine experience alterations in gene expression, and 2) whether these changes are elicited by a simulated herbicide mixture. Following a 7-d exposure to atrazine, female minnows were defeminized, whereas male frogs were feminized. The mixture did not elicit statistically significant effects in either species. Environ Toxicol Chem 2018;37:1182–1188.

Original languageEnglish (US)
Pages (from-to)1182-1188
Number of pages7
JournalEnvironmental Toxicology and Chemistry
Issue number4
Publication statusPublished - Apr 2018



  • Aquatic toxicology
  • Endocrine disruptor
  • Herbicide
  • Mixture
  • Pimephales promelas
  • Rana pipiens

ASJC Scopus subject areas

  • Environmental Chemistry
  • Health, Toxicology and Mutagenesis

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