Colorectal cancer in Egyptian patients under 40 years of age

Amr S. Soliman, Melissa L. Bondy, Bernard Levin, Mohamed R. Hamza, Kadry Ismail, Sohair Ismail, Hammam M. Hammam, Omar H. El-Hattab, Sanaa M. Kamal, Abdel Ghani A. Soliman, Laila A. Dorgham, R. Susie McPherson, R. Palmer Beasley

Research output: Contribution to journalArticle

93 Citations (Scopus)

Abstract

Although colorectal cancer is not a common cancer in Egypt, the age distribution of the disease shows that a high proportion occurs in children and adults under 40 years of age. We reviewed the records of 1,608 colorectal cancer patients treated in 4 cancer hospitals in Egypt during a period of 3 to 10 years. The hospitals in which about 85% of all colorectal cancer cases in Egypt were seen included Egypt's 2 major cancer centers, The National Cancer Institute (NCI) in Cairo and Tanta Cancer Center (TCC) in the mid-Nile Delta region, and 2 major university hospitals, Assiut University in South Egypt and Ain Shams University in Cairo. Our review showed that patients younger than 40 years represented 35.6% of all patients in the 4 cancer hospitals, and that these rates were similar among the hospitals and for the years reviewed. The male-to-female ratio increased from 1.0 to 1.7 for the age groups ranging from 0-9 and 30-39 years, and increased from 1.0 to 1.5 for the age groups ranging from 40-49 to over 60 years. More than half of all the patients had rectal tumors, and about 90% of the cancers were adenocarcinomas; 30.6% of patients younger than 40 years, compared with 13.8% of older patients, had mucin-producing tumors. This study confirmed the occurrence of a high colorectal cancer rate in young Egyptians, and it opens the door to future epidemiologic studies to identify causes and risk factors of this disease pattern in Egypt.

Original languageEnglish (US)
Pages (from-to)26-30
Number of pages5
JournalInternational Journal of Cancer
Volume71
Issue number1
DOIs
StatePublished - Apr 23 1997

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Egypt
Colorectal Neoplasms
Cancer Care Facilities
Neoplasms
Age Groups
Benzydamine
National Cancer Institute (U.S.)
Age Distribution
Mucins
Rectal Neoplasms
Epidemiologic Studies
Adenocarcinoma

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Soliman, A. S., Bondy, M. L., Levin, B., Hamza, M. R., Ismail, K., Ismail, S., ... Beasley, R. P. (1997). Colorectal cancer in Egyptian patients under 40 years of age. International Journal of Cancer, 71(1), 26-30. https://doi.org/10.1002/(SICI)1097-0215(19970328)71:1<26::AID-IJC6>3.0.CO;2-5

Colorectal cancer in Egyptian patients under 40 years of age. / Soliman, Amr S.; Bondy, Melissa L.; Levin, Bernard; Hamza, Mohamed R.; Ismail, Kadry; Ismail, Sohair; Hammam, Hammam M.; El-Hattab, Omar H.; Kamal, Sanaa M.; Soliman, Abdel Ghani A.; Dorgham, Laila A.; McPherson, R. Susie; Beasley, R. Palmer.

In: International Journal of Cancer, Vol. 71, No. 1, 23.04.1997, p. 26-30.

Research output: Contribution to journalArticle

Soliman, AS, Bondy, ML, Levin, B, Hamza, MR, Ismail, K, Ismail, S, Hammam, HM, El-Hattab, OH, Kamal, SM, Soliman, AGA, Dorgham, LA, McPherson, RS & Beasley, RP 1997, 'Colorectal cancer in Egyptian patients under 40 years of age', International Journal of Cancer, vol. 71, no. 1, pp. 26-30. https://doi.org/10.1002/(SICI)1097-0215(19970328)71:1<26::AID-IJC6>3.0.CO;2-5
Soliman, Amr S. ; Bondy, Melissa L. ; Levin, Bernard ; Hamza, Mohamed R. ; Ismail, Kadry ; Ismail, Sohair ; Hammam, Hammam M. ; El-Hattab, Omar H. ; Kamal, Sanaa M. ; Soliman, Abdel Ghani A. ; Dorgham, Laila A. ; McPherson, R. Susie ; Beasley, R. Palmer. / Colorectal cancer in Egyptian patients under 40 years of age. In: International Journal of Cancer. 1997 ; Vol. 71, No. 1. pp. 26-30.
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