Abstract
Dissociative phenomena are frequently experienced by psychologically traumatized people. However, little is known about the cognitive profiles of highly dissociative traumatized individuals, and corresponding patterns of neural connectivity when attentional networks are engaged in the context of emotion. One hundred seventeen traumatized women completed the multiscale dissociation inventory (MDI) and neuropsychological testing; MDI scores were used to classify high-and low-dissociative participants. Forty-six participants also underwent fMRI during performance of an attentional control task that incorporates emotionally distracting images (Affective Number Stroop; ANS). Compared to low-dissociative participants, high-dissociative participants demonstrated better performance on an executive functioning task (F1,111 = 4.64, p = .03), worse performance on a task of visual memory (F1,111 = 9.52, p = .003), and similar performance on all other neuropsychological measures. In addition, dissociative symptoms were negatively correlated with functional connectivity between the amygdala and right anterior insula in response to trauma-related ANS trials. These findings indicate that highly dissociative traumatized people experience difficulties with attentional control in the context of emotionally evocative stimuli, but in a neutral context, their overall cognitive profiles are similar to low-dissociative people. Highly dissociative participants also demonstrated weaker connectivity between the amygdala and insula in response to trauma-relevant images. Evocative, trauma-relevant stimuli appear to disrupt neutral networks involved with attention to salient cues and interoception in highly dissociative traumatized individuals.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 863-875 |
| Number of pages | 13 |
| Journal | Emotion |
| Volume | 19 |
| Issue number | 5 |
| DOIs | |
| State | Published - Aug 2019 |
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Keywords
- Amygdala
- Cognition
- Dissociation
- Emotion
- Fmri
ASJC Scopus subject areas
- Psychology(all)
Cite this
Cognitive and neural facets of dissociation in a traumatized population. / Fani, Negar; King, Tricia Z.; Powers, Abigail; Hardy, Raven A.; Siegle, Greg J.; Blair, Robert J.; Surapaneni, Sindhuja; Van Rooij, Sanne; Ressler, Kerry J.; Jovanovic, Tanja; Bradley, Bekh.
In: Emotion, Vol. 19, No. 5, 08.2019, p. 863-875.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cognitive and neural facets of dissociation in a traumatized population
AU - Fani, Negar
AU - King, Tricia Z.
AU - Powers, Abigail
AU - Hardy, Raven A.
AU - Siegle, Greg J.
AU - Blair, Robert J.
AU - Surapaneni, Sindhuja
AU - Van Rooij, Sanne
AU - Ressler, Kerry J.
AU - Jovanovic, Tanja
AU - Bradley, Bekh
PY - 2019/8
Y1 - 2019/8
N2 - Dissociative phenomena are frequently experienced by psychologically traumatized people. However, little is known about the cognitive profiles of highly dissociative traumatized individuals, and corresponding patterns of neural connectivity when attentional networks are engaged in the context of emotion. One hundred seventeen traumatized women completed the multiscale dissociation inventory (MDI) and neuropsychological testing; MDI scores were used to classify high-and low-dissociative participants. Forty-six participants also underwent fMRI during performance of an attentional control task that incorporates emotionally distracting images (Affective Number Stroop; ANS). Compared to low-dissociative participants, high-dissociative participants demonstrated better performance on an executive functioning task (F1,111 = 4.64, p = .03), worse performance on a task of visual memory (F1,111 = 9.52, p = .003), and similar performance on all other neuropsychological measures. In addition, dissociative symptoms were negatively correlated with functional connectivity between the amygdala and right anterior insula in response to trauma-related ANS trials. These findings indicate that highly dissociative traumatized people experience difficulties with attentional control in the context of emotionally evocative stimuli, but in a neutral context, their overall cognitive profiles are similar to low-dissociative people. Highly dissociative participants also demonstrated weaker connectivity between the amygdala and insula in response to trauma-relevant images. Evocative, trauma-relevant stimuli appear to disrupt neutral networks involved with attention to salient cues and interoception in highly dissociative traumatized individuals.
AB - Dissociative phenomena are frequently experienced by psychologically traumatized people. However, little is known about the cognitive profiles of highly dissociative traumatized individuals, and corresponding patterns of neural connectivity when attentional networks are engaged in the context of emotion. One hundred seventeen traumatized women completed the multiscale dissociation inventory (MDI) and neuropsychological testing; MDI scores were used to classify high-and low-dissociative participants. Forty-six participants also underwent fMRI during performance of an attentional control task that incorporates emotionally distracting images (Affective Number Stroop; ANS). Compared to low-dissociative participants, high-dissociative participants demonstrated better performance on an executive functioning task (F1,111 = 4.64, p = .03), worse performance on a task of visual memory (F1,111 = 9.52, p = .003), and similar performance on all other neuropsychological measures. In addition, dissociative symptoms were negatively correlated with functional connectivity between the amygdala and right anterior insula in response to trauma-related ANS trials. These findings indicate that highly dissociative traumatized people experience difficulties with attentional control in the context of emotionally evocative stimuli, but in a neutral context, their overall cognitive profiles are similar to low-dissociative people. Highly dissociative participants also demonstrated weaker connectivity between the amygdala and insula in response to trauma-relevant images. Evocative, trauma-relevant stimuli appear to disrupt neutral networks involved with attention to salient cues and interoception in highly dissociative traumatized individuals.
KW - Amygdala
KW - Cognition
KW - Dissociation
KW - Emotion
KW - Fmri
UR - http://www.scopus.com/inward/record.url?scp=85051988122&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85051988122&partnerID=8YFLogxK
U2 - 10.1037/emo0000466
DO - 10.1037/emo0000466
M3 - Article
C2 - 30124316
AN - SCOPUS:85051988122
VL - 19
SP - 863
EP - 875
JO - Emotion
JF - Emotion
SN - 1528-3542
IS - 5
ER -