Cocaine-Associated Ischemic Colitis

Jeffrey D. Linder, Klaus E. Mönkemüller, Isaac Raijman, Lawrence Johnson, Audrey J Lazenby, C. Mel Wilcox

Research output: Contribution to journalArticle

73 Citations (Scopus)

Abstract

Cocaine use can result in various gastrointestinal complications, including gastric ulcerations, retroperitoneal fibrosis, visceral infarction, intestinal ischemia, and gastrointestinal tract perforation. We report cocaine-associated colonic ischemia in three patients and review the literature. Including ours, 28 cases have been reported, with a mean patient age of 32.6 years (range, 23 to 47 years); 53.5% were men and 46.5% were women. The interval between drug ingestion and onset of symptoms varied from 1 hour to 2 days. Cocaine is a potentially life-threatening cause of ischemic colitis and should be included in the differential diagnosis of any young adult or middle-aged patient with abdominal pain and bloody diarrhea, especially in the absence of estrogen use or systemic disorders that can cause thromboembolic events, such as atrial fibrillation.

Original languageEnglish (US)
Pages (from-to)909-913
Number of pages5
JournalSouthern Medical Journal
Volume93
Issue number9
StatePublished - Sep 1 2000

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Ischemic Colitis
Cocaine
Ischemia
Retroperitoneal Fibrosis
Atrial Fibrillation
Infarction
Abdominal Pain
Gastrointestinal Tract
Young Adult
Diarrhea
Stomach
Estrogens
Differential Diagnosis
Eating
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Linder, J. D., Mönkemüller, K. E., Raijman, I., Johnson, L., Lazenby, A. J., & Wilcox, C. M. (2000). Cocaine-Associated Ischemic Colitis. Southern Medical Journal, 93(9), 909-913.

Cocaine-Associated Ischemic Colitis. / Linder, Jeffrey D.; Mönkemüller, Klaus E.; Raijman, Isaac; Johnson, Lawrence; Lazenby, Audrey J; Wilcox, C. Mel.

In: Southern Medical Journal, Vol. 93, No. 9, 01.09.2000, p. 909-913.

Research output: Contribution to journalArticle

Linder, JD, Mönkemüller, KE, Raijman, I, Johnson, L, Lazenby, AJ & Wilcox, CM 2000, 'Cocaine-Associated Ischemic Colitis', Southern Medical Journal, vol. 93, no. 9, pp. 909-913.
Linder JD, Mönkemüller KE, Raijman I, Johnson L, Lazenby AJ, Wilcox CM. Cocaine-Associated Ischemic Colitis. Southern Medical Journal. 2000 Sep 1;93(9):909-913.
Linder, Jeffrey D. ; Mönkemüller, Klaus E. ; Raijman, Isaac ; Johnson, Lawrence ; Lazenby, Audrey J ; Wilcox, C. Mel. / Cocaine-Associated Ischemic Colitis. In: Southern Medical Journal. 2000 ; Vol. 93, No. 9. pp. 909-913.
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