Clinical experience in the detection of coronary artery disease with myocardial contrast echocardiography

Flordeliza S. Villanueva, Thomas R. Porter, Feng Xie

Research output: Contribution to journalArticle

10 Scopus citations


Myocardial contrast enhancement following intravenous infusions or injections of perfluorocarbon-containing microbubbles has now been observed consistently in humans. Currently, the major challenge facing us is interpreting accurately what we see. The myocardial contrast patterns we observe have, thus far, been shown to detect myocardial perfusion abnormalities during dipyridamole, adenosine, and dobutamine stress echocardiography. They also have been shown to detect zones of no refiow following coronary revascularization in patients with acute myocardial infarction. These preliminary data will require validation in larger multicenter clinical studies.

Original languageEnglish (US)
Pages (from-to)399-407
Number of pages9
Issue number5
StatePublished - Jul 2002



  • Harmonics
  • Intermittent imaging
  • Microbubbles
  • Perfluorocarbons
  • Ultrasound

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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