Classification of non-Hodgkin lymphomas in Guatemala according to the World Health Organization system

Anamarija M. Perry, Hernan Molina-Kirsch, Bharat N. Nathwani, Jacques Diebold, Kenneth A. MacLennan, H. Konrad Mller-Hermelink, James Olen Armitage, Dennis D. Weisenburger

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The aim of this study is to report the relative frequencies of non-Hodgkin lymphoma (NHL) subtypes in Guatemala. A panel of five hematopathologists reviewed 226 consecutive biopsies and classified them according to the 2001 World Health Organization (WHO) classification. The 83 cases of diffuse large B-cell lymphoma (DLBCL) were further subclassified into germinal center B-cell-like (GCB) and non-GCB subtypes. Of the 226 cases, 194 (86%) were confirmed as NHL, including 169 (87%) B-cell and 25 (13%) T-or natural killer (NK)-cell NHL. The most common subtype was DLBCL (44.3%), and the most frequent subtype among T-and NK-cell NHL was extranodal NK/T-cell lymphoma, nasal type (7.8% of all NHL). A comparison of the frequencies of NHL subtypes between Guatemala and other parts of the world showed that Guatemala is most similar to the Middle East and Asia. However, there is no significant difference in the frequency of the DLBCL subtypes compared to North America and Europe.

Original languageEnglish (US)
Pages (from-to)1681-1688
Number of pages8
JournalLeukemia and Lymphoma
Volume52
Issue number9
DOIs
StatePublished - Sep 1 2011

Fingerprint

Guatemala
Non-Hodgkin's Lymphoma
Natural Killer T-Cells
Lymphoma, Large B-Cell, Diffuse
B-Lymphocytes
Germinal Center
Middle East
Far East
T-Cell Lymphoma
North America
Nose
Biopsy

Keywords

  • Guatemala
  • Non-Hodgkin lymphoma
  • diffuse large B-cell lymphoma
  • epidemiology

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

Cite this

Perry, A. M., Molina-Kirsch, H., Nathwani, B. N., Diebold, J., MacLennan, K. A., Mller-Hermelink, H. K., ... Weisenburger, D. D. (2011). Classification of non-Hodgkin lymphomas in Guatemala according to the World Health Organization system. Leukemia and Lymphoma, 52(9), 1681-1688. https://doi.org/10.3109/10428194.2011.584254

Classification of non-Hodgkin lymphomas in Guatemala according to the World Health Organization system. / Perry, Anamarija M.; Molina-Kirsch, Hernan; Nathwani, Bharat N.; Diebold, Jacques; MacLennan, Kenneth A.; Mller-Hermelink, H. Konrad; Armitage, James Olen; Weisenburger, Dennis D.

In: Leukemia and Lymphoma, Vol. 52, No. 9, 01.09.2011, p. 1681-1688.

Research output: Contribution to journalArticle

Perry, AM, Molina-Kirsch, H, Nathwani, BN, Diebold, J, MacLennan, KA, Mller-Hermelink, HK, Armitage, JO & Weisenburger, DD 2011, 'Classification of non-Hodgkin lymphomas in Guatemala according to the World Health Organization system', Leukemia and Lymphoma, vol. 52, no. 9, pp. 1681-1688. https://doi.org/10.3109/10428194.2011.584254
Perry AM, Molina-Kirsch H, Nathwani BN, Diebold J, MacLennan KA, Mller-Hermelink HK et al. Classification of non-Hodgkin lymphomas in Guatemala according to the World Health Organization system. Leukemia and Lymphoma. 2011 Sep 1;52(9):1681-1688. https://doi.org/10.3109/10428194.2011.584254
Perry, Anamarija M. ; Molina-Kirsch, Hernan ; Nathwani, Bharat N. ; Diebold, Jacques ; MacLennan, Kenneth A. ; Mller-Hermelink, H. Konrad ; Armitage, James Olen ; Weisenburger, Dennis D. / Classification of non-Hodgkin lymphomas in Guatemala according to the World Health Organization system. In: Leukemia and Lymphoma. 2011 ; Vol. 52, No. 9. pp. 1681-1688.
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