Chronic dietary fiber supplementation with wheat dextrin does not inhibit calcium and magnesium absorption in premenopausal and postmenopausal women

Laura AG Armas, K. Rafferty, A. Hospattankar, S. A. Abrams, R. P. Heaney

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

This placebo-controlled, randomized, crossover clinical study examined the effect of chronic wheat dextrin intake on calcium and magnesium absorption. Forty premenopausal and post menopausal women (mean ± SD age 49.9 ± 9.8 years) consumed wheat dextrin or placebo (15 g/day) for 2 weeks prior to 45calcium (45Ca) and 26magnesium (26Mg) absorption testing. After a standardized breakfast, serial blood and urine samples were obtained. The mean ± SD area under the curve from 0 to 9 h for 45Ca specific activity was 0.81 ± 0.21 for wheat dextrin and 0.82 ± 0.22 for placebo, showing that wheat dextrin had no effect on calcium absorption. The mean ± SD percentage excess of 26Mg/24Mg was 7.8% ± 2.1% for wheat dextrin and 7.9% ± 2.6% for placebo, showing that wheat dextrin had no effect on magnesium absorption. In conclusion, chronic wheat dextrin consumption did not inhibit calcium or magnesium absorption from the gastrointestinal tract in women.

Original languageEnglish (US)
Pages (from-to)1824-1833
Number of pages10
JournalJournal of International Medical Research
Volume39
Issue number5
DOIs
StatePublished - Jan 1 2011

Fingerprint

Dietary Fiber
Dietary Supplements
Magnesium
Triticum
Calcium
Placebos
Breakfast
caloreen
Cross-Over Studies
Area Under Curve
Gastrointestinal Tract
Blood
Urine
Testing

Keywords

  • Calcium Absorption
  • Fiber
  • Gastrointestinal
  • Magnesium Absorption
  • Placebo
  • Wheat Dextrin
  • Women

ASJC Scopus subject areas

  • Biochemistry
  • Cell Biology
  • Biochemistry, medical

Cite this

Chronic dietary fiber supplementation with wheat dextrin does not inhibit calcium and magnesium absorption in premenopausal and postmenopausal women. / Armas, Laura AG; Rafferty, K.; Hospattankar, A.; Abrams, S. A.; Heaney, R. P.

In: Journal of International Medical Research, Vol. 39, No. 5, 01.01.2011, p. 1824-1833.

Research output: Contribution to journalArticle

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