Chronic dietary fiber supplementation with wheat dextrin does not inhibit calcium and magnesium absorption in premenopausal and postmenopausal women

Laura A.G. Armas, K. Rafferty, A. Hospattankar, S. A. Abrams, R. P. Heaney

Research output: Contribution to journalArticle

4 Scopus citations


This placebo-controlled, randomized, crossover clinical study examined the effect of chronic wheat dextrin intake on calcium and magnesium absorption. Forty premenopausal and post menopausal women (mean ± SD age 49.9 ± 9.8 years) consumed wheat dextrin or placebo (15 g/day) for 2 weeks prior to 45calcium (45Ca) and 26magnesium (26Mg) absorption testing. After a standardized breakfast, serial blood and urine samples were obtained. The mean ± SD area under the curve from 0 to 9 h for 45Ca specific activity was 0.81 ± 0.21 for wheat dextrin and 0.82 ± 0.22 for placebo, showing that wheat dextrin had no effect on calcium absorption. The mean ± SD percentage excess of 26Mg/24Mg was 7.8% ± 2.1% for wheat dextrin and 7.9% ± 2.6% for placebo, showing that wheat dextrin had no effect on magnesium absorption. In conclusion, chronic wheat dextrin consumption did not inhibit calcium or magnesium absorption from the gastrointestinal tract in women.

Original languageEnglish (US)
Pages (from-to)1824-1833
Number of pages10
JournalJournal of International Medical Research
Issue number5
StatePublished - Jan 1 2011



  • Calcium Absorption
  • Fiber
  • Gastrointestinal
  • Magnesium Absorption
  • Placebo
  • Wheat Dextrin
  • Women

ASJC Scopus subject areas

  • Biochemistry
  • Cell Biology
  • Biochemistry, medical

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