Cholesterol Side-Chain Degradation and Cleft Palate Development in the Rat

J. A. Ursick, L. D. Israelsen, D. H. Shaw

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Abstract

The teratogenic action of cholesterol in developing rat fetuses was evaluated by the use of 14C-4, 3H-7, and 14C-26 labeled cholesterol. A comparison of radioactivity present in the fetuses indicated that the teratogenic activity of this steroid resides in a metabolite of cholesterol rather than in the intact molecule.

Original languageEnglish (US)
Pages (from-to)1421-1425
Number of pages5
JournalJournal of Dental Research
Volume51
Issue number5
DOIs
Publication statusPublished - Sep 1972

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ASJC Scopus subject areas

  • Dentistry(all)

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