Characterization of odorant patterns by comprehensive two-dimensional gas chromatography: A challenge in omic studies

Chiara Cordero, Johannes Kiefl, Stephen E. Reichenbach, Carlo Bicchi

Research output: Contribution to journalReview article

7 Citations (Scopus)

Abstract

Sensomics, like other “omics” fields, cuts across chemistry and biology and so requires holistic strategies capable of comprehensively mapping the set of all potential ligands (e.g., sensometabolome) that trigger the multimodal perception of food flavor. These complex mixtures when directed to odor receptors in the nose, define the so-called Chemical Odor Code. Analytical chemistry is challenged to comprehensively map the complex volatile fractions of real samples, including odorants and interferents, and define univocal odor patterns for correlative studies. This review critically discusses state-of-the-art research in the field of odorants and volatiles characterization in food by comprehensive two-dimensional gas chromatography, illustrating how hyphenation with mass spectrometry and olfactometry, accurate quantitation, suitable sample preparation, and dedicated data mining can capture essential information on odor patterns exploiting the higher level of information on sample sensory features.

Original languageEnglish (US)
Pages (from-to)364-378
Number of pages15
JournalTrAC - Trends in Analytical Chemistry
Volume113
DOIs
StatePublished - Apr 2019

Fingerprint

Odors
Gas chromatography
Flavors
Complex Mixtures
Mass spectrometry
Data mining
Ligands
Chemical analysis

Keywords

  • Chemical odor code
  • Comprehensive two-dimensional gas chromatography
  • Data mining
  • Multidimensional analytical platforms
  • Odor fingerprints
  • Sensomics

ASJC Scopus subject areas

  • Analytical Chemistry
  • Spectroscopy

Cite this

Characterization of odorant patterns by comprehensive two-dimensional gas chromatography : A challenge in omic studies. / Cordero, Chiara; Kiefl, Johannes; Reichenbach, Stephen E.; Bicchi, Carlo.

In: TrAC - Trends in Analytical Chemistry, Vol. 113, 04.2019, p. 364-378.

Research output: Contribution to journalReview article

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