Changes in predicted muscle coordination with subject-specific muscle parameters for individuals after stroke

Brian A. Knarr, Darcy S. Reisman, Stuart A. Binder-Macleod, Jill S. Higginson

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Muscle weakness is commonly seen in individuals after stroke, characterized by lower forces during a maximal volitional contraction. Accurate quantification of muscle weakness is paramount when evaluating individual performance and response to after stroke rehabilitation. The objective of this study was to examine the effect of subject-specific muscle force and activation deficits on predicted muscle coordination when using musculoskeletal models for individuals after stroke. Maximum force generating ability and central activation ratio of the paretic plantar flexors, dorsiflexors, and quadriceps muscle groups were obtained using burst superimposition for four individuals after stroke with a range of walking speeds. Two models were created per subject: one with generic and one with subject-specific activation and maximum isometric force parameters. The inclusion of subject-specific muscle data resulted in changes in the model-predicted muscle forces and activations which agree with previously reported compensation patterns and match more closely the timing of electromyography for the plantar flexor and hamstring muscles. This was the first study to create musculoskeletal simulations of individuals after stroke with subject-specific muscle force and activation data. The results of this study suggest that subject-specific muscle force and activation data enhance the ability of musculoskeletal simulations to accurately predict muscle coordination in individuals after stroke.

Original languageEnglish (US)
Article number321747
JournalStroke Research and Treatment
Volume2014
DOIs
StatePublished - 2014

Fingerprint

Stroke
Muscles
Muscle Weakness
Quadriceps Muscle
Electromyography

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Changes in predicted muscle coordination with subject-specific muscle parameters for individuals after stroke. / Knarr, Brian A.; Reisman, Darcy S.; Binder-Macleod, Stuart A.; Higginson, Jill S.

In: Stroke Research and Treatment, Vol. 2014, 321747, 2014.

Research output: Contribution to journalArticle

@article{7c7d83a72965430db0de8207543f1fb7,
title = "Changes in predicted muscle coordination with subject-specific muscle parameters for individuals after stroke",
abstract = "Muscle weakness is commonly seen in individuals after stroke, characterized by lower forces during a maximal volitional contraction. Accurate quantification of muscle weakness is paramount when evaluating individual performance and response to after stroke rehabilitation. The objective of this study was to examine the effect of subject-specific muscle force and activation deficits on predicted muscle coordination when using musculoskeletal models for individuals after stroke. Maximum force generating ability and central activation ratio of the paretic plantar flexors, dorsiflexors, and quadriceps muscle groups were obtained using burst superimposition for four individuals after stroke with a range of walking speeds. Two models were created per subject: one with generic and one with subject-specific activation and maximum isometric force parameters. The inclusion of subject-specific muscle data resulted in changes in the model-predicted muscle forces and activations which agree with previously reported compensation patterns and match more closely the timing of electromyography for the plantar flexor and hamstring muscles. This was the first study to create musculoskeletal simulations of individuals after stroke with subject-specific muscle force and activation data. The results of this study suggest that subject-specific muscle force and activation data enhance the ability of musculoskeletal simulations to accurately predict muscle coordination in individuals after stroke.",
author = "Knarr, {Brian A.} and Reisman, {Darcy S.} and Binder-Macleod, {Stuart A.} and Higginson, {Jill S.}",
year = "2014",
doi = "10.1155/2014/321747",
language = "English (US)",
volume = "2014",
journal = "Stroke Research and Treatment",
issn = "2090-8105",
publisher = "Hindawi Publishing Corporation",

}

TY - JOUR

T1 - Changes in predicted muscle coordination with subject-specific muscle parameters for individuals after stroke

AU - Knarr, Brian A.

AU - Reisman, Darcy S.

AU - Binder-Macleod, Stuart A.

AU - Higginson, Jill S.

PY - 2014

Y1 - 2014

N2 - Muscle weakness is commonly seen in individuals after stroke, characterized by lower forces during a maximal volitional contraction. Accurate quantification of muscle weakness is paramount when evaluating individual performance and response to after stroke rehabilitation. The objective of this study was to examine the effect of subject-specific muscle force and activation deficits on predicted muscle coordination when using musculoskeletal models for individuals after stroke. Maximum force generating ability and central activation ratio of the paretic plantar flexors, dorsiflexors, and quadriceps muscle groups were obtained using burst superimposition for four individuals after stroke with a range of walking speeds. Two models were created per subject: one with generic and one with subject-specific activation and maximum isometric force parameters. The inclusion of subject-specific muscle data resulted in changes in the model-predicted muscle forces and activations which agree with previously reported compensation patterns and match more closely the timing of electromyography for the plantar flexor and hamstring muscles. This was the first study to create musculoskeletal simulations of individuals after stroke with subject-specific muscle force and activation data. The results of this study suggest that subject-specific muscle force and activation data enhance the ability of musculoskeletal simulations to accurately predict muscle coordination in individuals after stroke.

AB - Muscle weakness is commonly seen in individuals after stroke, characterized by lower forces during a maximal volitional contraction. Accurate quantification of muscle weakness is paramount when evaluating individual performance and response to after stroke rehabilitation. The objective of this study was to examine the effect of subject-specific muscle force and activation deficits on predicted muscle coordination when using musculoskeletal models for individuals after stroke. Maximum force generating ability and central activation ratio of the paretic plantar flexors, dorsiflexors, and quadriceps muscle groups were obtained using burst superimposition for four individuals after stroke with a range of walking speeds. Two models were created per subject: one with generic and one with subject-specific activation and maximum isometric force parameters. The inclusion of subject-specific muscle data resulted in changes in the model-predicted muscle forces and activations which agree with previously reported compensation patterns and match more closely the timing of electromyography for the plantar flexor and hamstring muscles. This was the first study to create musculoskeletal simulations of individuals after stroke with subject-specific muscle force and activation data. The results of this study suggest that subject-specific muscle force and activation data enhance the ability of musculoskeletal simulations to accurately predict muscle coordination in individuals after stroke.

UR - http://www.scopus.com/inward/record.url?scp=84904134059&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84904134059&partnerID=8YFLogxK

U2 - 10.1155/2014/321747

DO - 10.1155/2014/321747

M3 - Article

C2 - 25093141

AN - SCOPUS:84904134059

VL - 2014

JO - Stroke Research and Treatment

JF - Stroke Research and Treatment

SN - 2090-8105

M1 - 321747

ER -