Changes in lipid classes of Drosophila melanogaster in response to selection for three stress traits

Li Ko, Lawrence Harshman, Sandra Hangartner, Ary Hoffmann, S. Kachman, Paul Black

Research output: Contribution to journalArticle

Abstract

Laboratory selection on environmental stress traits is an evolutionary approach that is informative in the context of understanding stress adaptation. Here we characterize changes in a lipidome of Drosophila melanogaster in lines selected for increased heat (elevated heat knockdown refractoriness), cold (decreased time to recover from chill-coma) and desiccation survival. Selection for desiccation resistance resulted in changes in multiple lipid classes used to characterize a lipidome. This included a decrease in triacylglycerols (TAGs) which is relevant to interpretation of storage lipid levels in previous D. melanogaster desiccation survival selection experiments. Chill-coma recovery rate selection was expected to show extensive changes in lipid classes, but only phosphatidic acids exhibited significant change. Selection for increased heat knockdown resistance resulted in a substantial change in the abundance of a class of lipids (diacylglycerols) which could play a role in mediating the heat shock response or result in an increase in neutral lipid mobilization.

Original languageEnglish (US)
Article number103890
JournalJournal of Insect Physiology
Volume117
DOIs
StatePublished - Aug 1 2019

Fingerprint

Drosophila melanogaster
Desiccation
Lipids
coma
Chills
Hot Temperature
lipids
Coma
heat
triacylglycerols
Lipid Mobilization
pesticide resistance
Heat-Shock Response
Phosphatidic Acids
Diglycerides
diacylglycerols
Triglycerides
acids

Keywords

  • Chill-coma
  • Desiccation
  • Drosophila melanogaster
  • Heat
  • Laboratory selection
  • Lipid metabolome
  • Lipid profile
  • Stress resistance
  • Stress selection

ASJC Scopus subject areas

  • Physiology
  • Insect Science

Cite this

Changes in lipid classes of Drosophila melanogaster in response to selection for three stress traits. / Ko, Li; Harshman, Lawrence; Hangartner, Sandra; Hoffmann, Ary; Kachman, S.; Black, Paul.

In: Journal of Insect Physiology, Vol. 117, 103890, 01.08.2019.

Research output: Contribution to journalArticle

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