Cerebrospinal fluid transthyretin in the neonate and blood–cerebrospinal fluid barrier permeability

Paul D. Larsen, Leonard Delallo

Research output: Contribution to journalArticle

16 Scopus citations


We measured transthyretin levels in the cerebrospinal fluid (CSF) of newborn infants, older children, patients with viral and bacterial meningitis, and adults with increased CSF protein levels. Neonatal CSF transthyretin levels are elevated disproportionately in comparison to levels in the other groups. We conclude that increased levels of transthyretin in the CSF of neonates are not explained by increased permeability of the blood–CSF barrier.

Original languageEnglish (US)
Pages (from-to)628-630
Number of pages3
JournalAnnals of Neurology
Issue number6
Publication statusPublished - Jun 1989


ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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