Central nervous system cancers, version 1.2015: Featured updates to the NCCN guidelines

Louis Burt Nabors, Jana Portnow, Mario Ammirati, Joachim Baehring, Henry Brem, Paul Brown, Nicholas Butowski, Marc C. Chamberlain, Robert A. Fenstermaker, Allan Friedman, Mark R. Gilbert, Jona Hattangadi-Gluth, Matthias Holdhoff, Larry Junck, Thomas Kaley, Ronald Lawson, Jay S. Loeffler, Mary P. Lovely, Paul L. Moots, Maciej M. MrugalaHerbert B. Newton, Ian Parney, Jeffrey J. Raizer, Lawrence Recht, Nicole Shonka, Dennis C. Shrieve, Allen K. Sills, Lode J. Swinnen, David Tran, Nam Tran, Frank D. Vrionis, Stephanie Weiss, Patrick Yung Wen, Nicole McMillian, Anita M. Engh

Research output: Contribution to journalReview article

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Abstract

The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Central Nervous System (CNS) Cancers provide interdisciplinary recommendations for managing adult CNS cancers. Primary and metastatic brain tumors are a heterogeneous group of neoplasms with varied outcomes and management strategies. These NCCN Guidelines Insights summarize the NCCN CNS Cancers Panel's discussion and highlight notable changes in the 2015 update. This article outlines the data and provides insight into panel decisions regarding adjuvant radiation and chemotherapy treatment options for high-risk newly diagnosed low-grade gliomas and glioblastomas. Additionally, it describes the panel's assessment of new data and the ongoing debate regarding the use of alternating electric field therapy for high-grade gliomas.

Original languageEnglish (US)
Pages (from-to)1191-1202
Number of pages12
JournalJNCCN Journal of the National Comprehensive Cancer Network
Volume13
Issue number10
DOIs
StatePublished - Oct 1 2015

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ASJC Scopus subject areas

  • Oncology

Cite this

Nabors, L. B., Portnow, J., Ammirati, M., Baehring, J., Brem, H., Brown, P., Butowski, N., Chamberlain, M. C., Fenstermaker, R. A., Friedman, A., Gilbert, M. R., Hattangadi-Gluth, J., Holdhoff, M., Junck, L., Kaley, T., Lawson, R., Loeffler, J. S., Lovely, M. P., Moots, P. L., ... Engh, A. M. (2015). Central nervous system cancers, version 1.2015: Featured updates to the NCCN guidelines. JNCCN Journal of the National Comprehensive Cancer Network, 13(10), 1191-1202. https://doi.org/10.6004/jnccn.2015.0148