Cells That Resorb Bone

Peter Felix Coccia

Research output: Contribution to journalEditorial

15 Citations (Scopus)

Abstract

Skeletal remodeling is an ongoing process of synthesis of bone matrix coupled with bone resorption, which is regulated by a variety of hormones and other factors. Bone formation and its regulation have recently been reviewed in the Journal.1 Bone resorption, which is necessary not only for skeletal growth and remodeling but also for the regulation of serum calcium and phosphate concentrations, is stimulated by parathyroid hormone, 1,25-dihydroxyvitamin D3 (calcitriol), prostaglandin E2, and the lymphokine osteoclast-activating factor. It is inhibited by calcitonin and by diphosphonate compounds and mithramycin. Excessive bone resorption occurs in a variety of systemic.

Original languageEnglish (US)
Pages (from-to)456-458
Number of pages3
JournalNew England Journal of Medicine
Volume310
Issue number7
DOIs
StatePublished - Feb 16 1984

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Bone Resorption
Calcitriol
Bone and Bones
Plicamycin
Bone Matrix
Lymphokines
Diphosphonates
Calcitonin
Parathyroid Hormone
Dinoprostone
Osteogenesis
Hormones
Growth
Serum

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Cells That Resorb Bone. / Coccia, Peter Felix.

In: New England Journal of Medicine, Vol. 310, No. 7, 16.02.1984, p. 456-458.

Research output: Contribution to journalEditorial

Coccia, Peter Felix. / Cells That Resorb Bone. In: New England Journal of Medicine. 1984 ; Vol. 310, No. 7. pp. 456-458.
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