Catecholamine infusion in the unanesthetized goat lymph fistula model

Joseph Clarke Stothert Jr, Robert Winn, Brad Nadir, C. J. Carrico, Jacob Hildebrandt

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

This study has demonstrated in an awake goat the differential effects of infusing low dose epinephrine and norepinephrine. Epinephrine increases pulmonary fluid exchange, possibly as a result of β stimulation to the heart; whereas norepinephrine results in little change in pulmonary fluid balance, primarily affecting vascular vasoreactivity. This study underscores the importance of testing drug responses in awake animal models.

Original languageEnglish (US)
Pages (from-to)367-371
Number of pages5
JournalJournal of Surgical Research
Volume34
Issue number4
DOIs
StatePublished - Jan 1 1983

Fingerprint

Lymph
Goats
Epinephrine
Fistula
Catecholamines
Norepinephrine
Lung
Water-Electrolyte Balance
Blood Vessels
Animal Models
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Surgery

Cite this

Catecholamine infusion in the unanesthetized goat lymph fistula model. / Stothert Jr, Joseph Clarke; Winn, Robert; Nadir, Brad; Carrico, C. J.; Hildebrandt, Jacob.

In: Journal of Surgical Research, Vol. 34, No. 4, 01.01.1983, p. 367-371.

Research output: Contribution to journalArticle

Stothert Jr, Joseph Clarke ; Winn, Robert ; Nadir, Brad ; Carrico, C. J. ; Hildebrandt, Jacob. / Catecholamine infusion in the unanesthetized goat lymph fistula model. In: Journal of Surgical Research. 1983 ; Vol. 34, No. 4. pp. 367-371.
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