Catalytic iron-mediated enediene carbocyclizations: The enantioselective synthesis of a homologue of the alkaloid (-)-protoemetinol

James M. Takacs, Scott C. Boito

Research output: Contribution to journalArticle

32 Scopus citations


The efficient enantioselective synthesis of the benzoquinolizidine 2 highlights the utility of the stereoselective iron-catalyzed cyclization of enedienes and affords the opportunity to prepare analogues of protoemetinol, psychotrine, and related natural products.

Original languageEnglish (US)
Pages (from-to)2941-2944
Number of pages4
JournalTetrahedron Letters
Issue number17
StatePublished - Apr 24 1995


ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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