Catalytic iron-mediated enediene carbocyclizations

The enantioselective synthesis of a homologue of the alkaloid (-)-protoemetinol

James M Takacs, Scott C. Boito

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

The efficient enantioselective synthesis of the benzoquinolizidine 2 highlights the utility of the stereoselective iron-catalyzed cyclization of enedienes and affords the opportunity to prepare analogues of protoemetinol, psychotrine, and related natural products.

Original languageEnglish (US)
Pages (from-to)2941-2944
Number of pages4
JournalTetrahedron Letters
Volume36
Issue number17
DOIs
StatePublished - Apr 24 1995

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Cyclization
Biological Products
Alkaloids
Iron
protoemetinol
psychotrine

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Catalytic iron-mediated enediene carbocyclizations : The enantioselective synthesis of a homologue of the alkaloid (-)-protoemetinol. / Takacs, James M; Boito, Scott C.

In: Tetrahedron Letters, Vol. 36, No. 17, 24.04.1995, p. 2941-2944.

Research output: Contribution to journalArticle

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