Case report: Ivermectin and Albendazole Plasma concentrations in a patient with disseminated strongyloidiasis on extracorporeal membrane oxygenation and continuous renal replacement therapy

Carl Boodman, Yashpal S. Chhonker, Daryl J Murry, Allison Mah, Jennifer Grant, Theodore Steiner, Michael Libman, Cesilia Nishi, Marthe Charles

Research output: Contribution to journalArticle

Abstract

Disseminated strongyloidiasis is often fatal, despite treatment with oral albendazole and parenteral ivermectin (IVM). Here, we report elevated plasma IVM and albendazole sulfoxide concentrations in the context of extra-corporeal membrane oxygenation and continuous renal replacement therapyinapatient with disseminated strongyloidiasis treated with subcutaneous IVM and nasogastric albenzadole. Despite elevated drug plasma concentrations, live filariform larvae were detected in endotracheal aspirates after 2 weeks of treatment.

Original languageEnglish (US)
Pages (from-to)1194-1197
Number of pages4
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume99
Issue number5
DOIs
StatePublished - Jan 1 2018

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Strongyloidiasis
Albendazole
Ivermectin
Extracorporeal Membrane Oxygenation
Renal Replacement Therapy
Larva
Kidney
Membranes
Therapeutics
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Parasitology
  • Virology
  • Infectious Diseases

Cite this

Case report : Ivermectin and Albendazole Plasma concentrations in a patient with disseminated strongyloidiasis on extracorporeal membrane oxygenation and continuous renal replacement therapy. / Boodman, Carl; Chhonker, Yashpal S.; Murry, Daryl J; Mah, Allison; Grant, Jennifer; Steiner, Theodore; Libman, Michael; Nishi, Cesilia; Charles, Marthe.

In: American Journal of Tropical Medicine and Hygiene, Vol. 99, No. 5, 01.01.2018, p. 1194-1197.

Research output: Contribution to journalArticle

Boodman, Carl ; Chhonker, Yashpal S. ; Murry, Daryl J ; Mah, Allison ; Grant, Jennifer ; Steiner, Theodore ; Libman, Michael ; Nishi, Cesilia ; Charles, Marthe. / Case report : Ivermectin and Albendazole Plasma concentrations in a patient with disseminated strongyloidiasis on extracorporeal membrane oxygenation and continuous renal replacement therapy. In: American Journal of Tropical Medicine and Hygiene. 2018 ; Vol. 99, No. 5. pp. 1194-1197.
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